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Advances in Pharmacology, Volume 46 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Advances in Pharmacology, Volume 46 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R6,201 Discovery Miles 62 010 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.
Key Features
* This volume includes reviews on some of the hottest topics in pharmacology, including:
* Multidrug resistance and the "MDR"1 gene in gene therapy
* Regulation of calcium channels in epithelial cells
* Gene therapy and vascular disease
* Potential therapeutic applications for Heparin
* Calcium channel blockers
* Antithrombotic agents
* Regulation of potassium channels in epithelial cells

Cumulative Subject Index, Volume 45 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Cumulative Subject Index, Volume 45 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R6,202 Discovery Miles 62 020 Ships in 12 - 17 working days

Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. For easy reference, this volume provides a cumulative subject index covering Volumes 25-44.

Advances in Pharmacology, Volume 44 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Advances in Pharmacology, Volume 44 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R6,227 Discovery Miles 62 270 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

Drug-Drug Interactions: Scientific and Regulatory Perspectives, Volume 43 (Hardcover): J.Thomas August, Ferid Murad, M.W.... Drug-Drug Interactions: Scientific and Regulatory Perspectives, Volume 43 (Hardcover)
J.Thomas August, Ferid Murad, M.W. Anders, Joseph T. Coyle; Volume editing by Albert Li
R6,203 Discovery Miles 62 030 Ships in 12 - 17 working days

Drug-Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug-drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug-drug interactions, the prediction of drug-drug interaction potential of new drugs, and the avoidance of clinically significant drug-drug interaction in patients.
Key Features
* Provides useful references on the science of drug-drug interactions
* Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint
* Contains original data from academic and industrial laboratories
* Presents an overview of regulatory agency positions

Advances in Pharmacology, Volume 37 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Advances in Pharmacology, Volume 37 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R5,845 Discovery Miles 58 450 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

Advances in Pharmacology, Volume 35 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Advances in Pharmacology, Volume 35 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R5,842 Discovery Miles 58 420 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

Advances in Pharmacology, Volume 30 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Advances in Pharmacology, Volume 30 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R1,743 Discovery Miles 17 430 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

DNA Topoisomearases: Biochemistry and Molecular Biology, Volume 29A (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad,... DNA Topoisomearases: Biochemistry and Molecular Biology, Volume 29A (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle; Volume editing by Leroy F. Liu
R1,734 Discovery Miles 17 340 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

Advances in Pharmacology, Volume 28 (Hardcover): J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle Advances in Pharmacology, Volume 28 (Hardcover)
J.Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle
R1,738 Discovery Miles 17 380 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds, Volume 27 (Hardcover): J.Thomas August, Ferid Murad Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds, Volume 27 (Hardcover)
J.Thomas August, Ferid Murad; Volume editing by M.W. Anders, Wolfgang Dekant
R1,756 Discovery Miles 17 560 Ships in 12 - 17 working days

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
Conjugation reactions have long been associated with the detoxification of xenobiotics. Recent studies suggest that Phase II reactions are an important mechanism for the bioactivation of xenobiotics.
This special volume of Advances in Pharmacology features a two-color dust jacket.
Key Features
* Summarizes the most recent information on:
* Xenobiotic conjugation
* Drug toxicity, hypersensitivity, and targeting
Chemical carcinogenesis
* Glutathione-, sulfate conjugate-, and glucuranide conjugate-dependent toxicity
* Bioactivation and bioconversion

Cyclic GMP: Synthesis, Metabolism, and Function, Volume 26 (Hardcover): J.Thomas August, M.W. Anders Cyclic GMP: Synthesis, Metabolism, and Function, Volume 26 (Hardcover)
J.Thomas August, M.W. Anders; Volume editing by Ferid Murad
R1,735 Discovery Miles 17 350 Ships in 12 - 17 working days

This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed.
Key Features
* Isoforms of guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis
* Cyclic GMP-dependent protein kinase
* Hormones and ligands that regulate GMP formation and/or metabolism
* Effects of cyclic GMP on other second messengers and some functions such as smooth muscle relaxation and ion transport
* Clinical studies with cyclic GMP and atrial natriuretic peptide
* Important questions and experiments for the future

HIV I: Molecular Biology and Pathogenesis: Clinical Applications, Volume 56 (Hardcover, 2nd edition): J.Thomas August, Ferid... HIV I: Molecular Biology and Pathogenesis: Clinical Applications, Volume 56 (Hardcover, 2nd edition)
J.Thomas August, Ferid Murad; Volume editing by Kuan-Teh Jeang
R5,227 Discovery Miles 52 270 Ships in 12 - 17 working days

Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad: "HIV-1: Molecular Biology and Pathogenesis, 2E." Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus.
* The latest developments in HIV-vaccine research
* New concepts in the discovery and design of novel anti-HIV drugs

HIV-1: Molecular Biology and Pathogenesis: Viral Mechanisms, Volume 55 (Hardcover, 2nd edition): Kuan-Teh Jeang, J.Thomas... HIV-1: Molecular Biology and Pathogenesis: Viral Mechanisms, Volume 55 (Hardcover, 2nd edition)
Kuan-Teh Jeang, J.Thomas August, Ferid Murad
R5,510 Discovery Miles 55 100 Ships in 12 - 17 working days

This volume covers the latest advances in the mechanisms of pathogenesis of the HIV-1 virus on target cells. Its companion volume, Advances in Pharmacology 56, shows how new developments in understanding the virus translate to the clinical setting.

HIV I: Molecular Biology and Pathogenesis: Clinical Applications, Volume 49 (Hardcover): J.Thomas August, Ferid Murad HIV I: Molecular Biology and Pathogenesis: Clinical Applications, Volume 49 (Hardcover)
J.Thomas August, Ferid Murad; Volume editing by Kuan-Teh Jeang
R5,512 Discovery Miles 55 120 Ships in 12 - 17 working days

The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.
The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.
Key Features
* Detailed insights into viral packaging, expression, and assembly
* Mechanistic understanding of how HIV interacts with receptors and infects cells
* Delineation of virally encoded regulatory processes unique to HIV
* Clinical Applications:
* An updated review of current chemotherapeutics for HIV
* New concepts in the discovery and design of novel anti-HIV drugs
* The latest developments in HIV-vaccine research

Herbal Medicine - Back to the Future: Volume 3, Cancer Therapy (Paperback): Atta-ur Rahman, Ka Bian, Ferid Murad Herbal Medicine - Back to the Future: Volume 3, Cancer Therapy (Paperback)
Atta-ur Rahman, Ka Bian, Ferid Murad
R2,460 R2,323 Discovery Miles 23 230 Save R137 (6%) Ships in 10 - 15 working days
Herbal Medicine - Back to the Future: Volume 2, Vascular Health (Paperback): Atta-ur Rahman, Ka Bian, Ferid Murad Herbal Medicine - Back to the Future: Volume 2, Vascular Health (Paperback)
Atta-ur Rahman, Ka Bian, Ferid Murad
R2,689 R2,529 Discovery Miles 25 290 Save R160 (6%) Ships in 10 - 15 working days
Dr. Murad and Nitric Oxide (Paperback): Daniel Cheng Chen, Ferid Murad Dr. Murad and Nitric Oxide (Paperback)
Daniel Cheng Chen, Ferid Murad
R413 Discovery Miles 4 130 Ships in 10 - 15 working days

The Nobel-Prize-winning discoveries of Dr. Ferid Murad brought nitric oxide into widespread recognition as the "star molecule" of the twentieth century, particularly in the area of human health. The actions of nitric oxide in the body touch almost every important aspect of physical well-being. For the first time, Dr. Murad and Dr. Daniel Chen present a clear description of the physiological functions of nitric oxide in language that everyone can understand. They then show us how to identify early signs of a broad range of nitric-oxide-related illness spanning the gamut from cardiovascular disease through neurological problems to sexual and reproductive issues. They reveal specific steps that we can take to improve and sustain vitality by promoting the action of nitric oxide within our bodies, and they show us how to maximize the amazing effects of nitric oxide so that we can live longer, happier and healthier lives.

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