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The two main goals of the symposium upon which this volume is based
were 1) to cement together knowledge presently available in the
field of antibodies to steroids and obtainable only under separate
covers in different journals and books, and 2) to present new data
which could lead to a more complete understanding of physiologic
phenomena like those occurring during the menstrual cycle, or to
the elucidation of the mechanisms involved in steroid-protection
interaction, or to the practical application of immunologic
techniques to measurements of steroid hor mones. These techniques
are extremely sensitive and can measure levels of steroid on the
same order of magnitude as the radioisotope methods. However, the
latter are much more laborious and costly which limits their use in
many cases to the research laboratory. But the immunologic
techniques generally classified as radioimmunoassay, are fraught
with difficulties and problems which must be overcome. Fortunately,
perhaps, the subject of immunologic techniques as applied to
steroid determination is the child of radioimmunoassay of proteins,
so to speak. Many of the problems which confront the former have
been resolved in the latter instance. Thus, we are in an
advantageous position because we are aware of the biologic and
technical problems of the earlier radioimmunoassay techniques.
Similar experiences have been reported in the book about the use of
immunologic techniques for determination of steroid hormones.
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