Designed to encourage and facilitate students' critical thinking skills, curiosity, and understanding of different science careers, this work presents a wide range of engaging real-life stories from successful and dedicated science professionals from diverse scientific disciplines. Providing a comprehensive overview of science careers and highlighting the skills needed for success, the author has designed this guide specifically to prepare high school, undergraduate and graduate students for the multiple roles they will encounter as science professionals upon graduation. Offering a thoughtful fusion of experiences, wisdom, commentaries, and practical advice for students as they consider a career in the sciences, this resource details specific strategies and crucial information that are most appropriate for a successful science career.