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Gene Correction - Methods and Protocols (Hardcover, 2014 ed.): Francesca Storici Gene Correction - Methods and Protocols (Hardcover, 2014 ed.)
Francesca Storici
R4,352 Discovery Miles 43 520 Ships in 10 - 15 working days

Gene correction is a technology that gives us the tools for both repairing and mutating DNA, for discovering gene functions and for engineering new genetic variants. Gene Correction: Methods and Protocols provides a user friendly, detailed and up-to-date collection of strategies and methodologies utilized for generating specific sequence changes in the DNA of cells in the laboratory, while also tackling the major problems that the field of gene correction faces. This volume brings together many experts in the field of gene correction to disclose a wide and varied array of specific gene correction protocols for engineering mutations in DNA, for delivering correcting DNA to target cells, and for improving the accuracy and safety of the gene correction process. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Gene Correction: Methods and Protocols seeks to serve scientists of all backgrounds interested in the area of gene targeting/recombination/therapy.

DNA Repair - On the Pathways to Fixing DNA Damage and Errors (Hardcover): Francesca Storici DNA Repair - On the Pathways to Fixing DNA Damage and Errors (Hardcover)
Francesca Storici
R4,074 R3,802 Discovery Miles 38 020 Save R272 (7%) Ships in 10 - 15 working days
Gene Correction - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2014): Francesca Storici Gene Correction - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2014)
Francesca Storici
R4,695 Discovery Miles 46 950 Ships in 10 - 15 working days

Gene correction is a technology that gives us the tools for both repairing and mutating DNA, for discovering gene functions and for engineering new genetic variants. Gene Correction: Methods and Protocols provides a user friendly, detailed and up-to-date collection of strategies and methodologies utilized for generating specific sequence changes in the DNA of cells in the laboratory, while also tackling the major problems that the field of gene correction faces. This volume brings together many experts in the field of gene correction to disclose a wide and varied array of specific gene correction protocols for engineering mutations in DNA, for delivering correcting DNA to target cells, and for improving the accuracy and safety of the gene correction process. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Gene Correction: Methods and Protocols seeks to serve scientists of all backgrounds interested in the area of gene targeting/recombination/therapy.

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