Advances in Genetics has established itself as an outstanding vehicle for the dissemination of research results in genetics. Once again, authoritative papers are presented here, beginning with a review by Rai and Black highlighting the salient features of mosquito genomes and their evolution. The recent progress which has been made by the cloning and characterization of two cooperating partners of the Neurospora blue light signal transduction chain is presented by Linden, Balario, Arpaia, and Macino. The emergence of the concept of X-linked mental retardation (XLMR) is discussed by Neri and Chiurazzi, as well as epidemiologic data and XLMR gene updates. In chapter 4, Mahato, Smith, and Rolland provide insights into the potentials of plasmid-based gene therapy and critical evaluation of gene delivery sciences and clinical applications of gene medicines. Kathleen Triman completes the volume with an outline of the genetic strategies designed to improve our understanding of the structure and function of 23S ribosomal RNA in "E. coli."

This volume continues to present articles which should be of interest to both human and molecular geneticists. It begins with a review of the various classifications, mechanisms and molecular diagnostic tests of peroneal muscular atrophy (or CMT). An examination of the importance of tumour suppressor genes in human cancer and a number of the significant problems faced by cancer geneticists is included. The notion of genetic redundancy and whether true functional redundancy can exist is investigated and a discussion of recent findings on speciation and the role of hybrid inviability in "drosophila" is conducted. This book also reviews the effects of metal-regulated gene expression in cellular metabolism, pathogenicity and toxicity. In addition, it provides descriptions of chromosomal translocations in Neuraospora and other fungi for use in executing genetic crosses.

Advances in Genetics increases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
Genetics, the science of heredity, lies at the heart of biology, and many diseases are impacted by an individuals genetic make-up. The field of genetics is rapidly evolving and new medical break-throughs are occurring as a result of advances in knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. This volume of Advances in Genetics contains the following articles: Targeted Expression of Tetanus Toxin; Germ-line Transformants Spreading Out to Many Insect Species; Genes Mediating Sex-Specific Behaviors in "Drosophila"; and Evolutionary Analyses of Genes and Their Functional Implications.