This book discusses 'how' to respectfully and responsibly include pregnant women in clinical research. In sharp contrast, the existing literature predominantly focuses on the reasons 'why' the inclusion of pregnant women in clinical research is necessary - viz., to develop effective treatments for women during pregnancy, to promote fetal safety, to reduce harm to women and fetuses from suboptimal care, and to allow access to the benefits of research participation. This book supports the shift to a new default position, whereby pregnant women are included in clinical research unless researchers argue convincingly for their exclusion. This shift raises many as yet unexplored ethical and policy questions about existing barriers to the equitable inclusion of pregnant women in research. This book is original in three key ways. First, it presents an unparalleled depth of analysis of the ethics of research with pregnant women, bringing together many of the key authors in this field as well as experts in research ethics and in vulnerability who have not previously applied their work to pregnant women. Second, it includes innovative theoretical work in ethics and disease specific case studies that highlight the current complexity and future challenges of research involving pregnant women. Third, the book brings together authors who argue both for and against including more pregnant women in formal clinical trials.

Over a decade ago, the field of bioethics was established in response to the increased control over the design of living organisms afforded by both medical genetics and biotechnology. Since its introduction, bioethics has become established as an academic discipline with journals and professional societies, is covered regularly in the media, and affects people everyday around the globe. In response to the increasing need for information about medical genetics and biotechnology as well as the ethical issues these fields raise, Sheed & Ward proudly presents the Readings in Bioethics Series. Edited by Thomas A. Shannon, the series provides anthologies of critical essays and reflections by leading ethicists in four pivotal areas: reproductive technologies, genetic technologies, death and dying, and health care policy. The goal of this series is twofold: first, to provide a set of readers on thematic topics for introductory or survey courses in bioethics or for courses with a particular theme or time limitation. Second, each of the readers in this series is designed to help students focus more thoroughly and effectively on specific topics that flesh out the ethical issues at the core of bioethics. The series is also highly accessible to general readers interested in bioethics. This volume collects critical essays by leading scholars on issues in biotechnology, genetic counseling and the disabled, population screening, race-based gamete selection, stem cell research, reproductive freedom and preimplantation diagnosis, procreation for organ and tissue procurement, and other critical areas where moral and ethical dilemmas are emerging from new and existing practices, policy, and legislation.

Speaking from and to the growing movement among academics to become involved with 'socially-engaged' work, this volume presents first-person case studies of attempts to fix serious ethical problems in medical practice and research. It highlights the critical difference between the pundit approach to bioethics and the interventional approach - the talkers and the doers - and points to how abused and damaged the doers often end up. Chapters cover a diverse set of topics, including the troubling influence of for-profit businesses on public health policy, the politics of exposing histories of unjust medical research, the challenges of patient rights' work in sexuality and reproduction, collaborations between NGOs and academics, methods for changing entrenched yet harmful medical practices, engaging public policy through educating governmental leaders, and whistleblowing. The trending interest in the interplay of academia and advocacy and the growing importance of 'socially-engaged' work by academics make this a timely and much-needed resource.

A leading bioethicist offers critical insights into the scientific, ethical, and political implications of human genome editing. Designer babies, once found only in science fiction, have become a reality. We are entering a new era of human evolution with the advent of a technology called CRISPR, which allows scientists to modify our genes. Although CRISPR shows great promise for therapeutic use, it raises thorny ethical, legal, political, and societal concerns because it can be used to make permanent changes to future generations. What if changes intended for the good turn out to have unforeseen negative effects? What if the divide between the haves and have-nots widens as a result? Who decides whether we genetically modify human beings and, if so, how? Francoise Baylis insists that we must all have a role in determining our future as a species. The scientists who develop and use genome-editing tools should not be the only ones making decisions about future uses of the technology. Such decisions must be the fruit of a broad societal consensus. Baylis argues that it is in our collective interest to assess and steer the development and implementation of biomedical technologies. Members of the public with different interests and diverse perspectives must be among the decision makers; only in this way can we ensure that societal concerns are taken into account and that responsible decisions are made. We must be engaged and informed, think critically, and raise our voices as we create our future together. Sharp, rousing, timely, and thought-provoking, Altered Inheritance is essential reading. The future of humanity is in our hands.

Speaking from and to the growing movement among academics to become involved with 'socially-engaged' work, this volume presents first-person case studies of attempts to fix serious ethical problems in medical practice and research. It highlights the critical difference between the pundit approach to bioethics and the interventional approach - the talkers and the doers - and points to how abused and damaged the doers often end up. Chapters cover a diverse set of topics, including the troubling influence of for-profit businesses on public health policy, the politics of exposing histories of unjust medical research, the challenges of patient rights' work in sexuality and reproduction, collaborations between NGOs and academics, methods for changing entrenched yet harmful medical practices, engaging public policy through educating governmental leaders, and whistleblowing. The trending interest in the interplay of academia and advocacy and the growing importance of 'socially-engaged' work by academics make this a timely and much-needed resource.

This book discusses 'how' to respectfully and responsibly include pregnant women in clinical research. In sharp contrast, the existing literature predominantly focuses on the reasons 'why' the inclusion of pregnant women in clinical research is necessary - viz., to develop effective treatments for women during pregnancy, to promote fetal safety, to reduce harm to women and fetuses from suboptimal care, and to allow access to the benefits of research participation. This book supports the shift to a new default position, whereby pregnant women are included in clinical research unless researchers argue convincingly for their exclusion. This shift raises many as yet unexplored ethical and policy questions about existing barriers to the equitable inclusion of pregnant women in research. This book is original in three key ways. First, it presents an unparalleled depth of analysis of the ethics of research with pregnant women, bringing together many of the key authors in this field as well as experts in research ethics and in vulnerability who have not previously applied their work to pregnant women. Second, it includes innovative theoretical work in ethics and disease specific case studies that highlight the current complexity and future challenges of research involving pregnant women. Third, the book brings together authors who argue both for and against including more pregnant women in formal clinical trials.

Public attention on embryo research has never been greater. Modern reproductive medicine technology and the use of embryos to generate stem cells ensure that this will continue to be a topic of debate and research across many disciplines. This multidisciplinary book explores the concept of a 'healthy' embryo, its implications on the health of children and adults, and how perceptions of what constitutes child and adult health influence the concept of embryo 'health'. The concept of human embryo health is considered from preconception to pre-implantation genetic diagnosis to recent foetal surgical approaches. Burgeoning capacities in both genetic and reproductive science and their clinical implications have catalysed the necessity to explore the concept of a 'healthy' embryo. The authors are from five countries and 13 disciplines in the social sciences, humanities, biological sciences and medicine, ensuring that the book has a broad coverage and approach.

Medical issues affecting health care have become everyday media events. In response to mounting public concern, growing numbers of bioethicists are being appointed to medical school faculties and public policy panels. However the ideas voiced in these forums are seldom informed by feminist perspectives. In this important book, a distinguished group of feminist scholars and activists discuss crucial bioethics topics in a feminist light. Among the subjects explored are the care/justice debates, transforming bioethics, practice, and reproduction. The book also covers less commonly discussed issues, such as culturally appropriate responses to reproductive health problems in developing countries.