Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique multi-modality approach to management of all types of primary and secondary liver tumors. The biology of liver cancers, state of the art radiologic imaging and novel, non-surgical interventional strategies are given. There is an in depth analysis of surgical options including transplantation, resection, interstitial ablation techniques and liver-directed chemotherapy for hepatocellular carcinoma, bile duct cancers, and colorectal and neuroendocrine liver metastases. Because of the unique and comprehensive examination of liver tumors, this work is an excellent resource for surgical, transplant and medical oncologists, surgeons, gastroenterologists, and radiologists.

With one exception, all of the papers in this volume were originally presented at a conference held in April, 1978, at The Ohio State University. The excep tion is the paper by Wilfrid Sellars, which is a revised version of a paper he originally published in the Journal of Philosophy, 1973. However, the present version of Sellars' paper is so thoroughly changed from its original, that it is now virtually a new paper. None of the other nine papers has been published previously. The bibliography, prepared by Nancy Kelsik, is very extensive and it is tempting to think that it is complete. But I believe that virtual com pleteness is more likely to prove correct. The conference was made possible by grants from the College of Human ities and the Graduate School, Ohio State University, as well as by a grant from the Philosophy Department. On behalf of the contributors, I want to thank these institutions for their support. I also want to thank Marshall Swain and Robert Turnbu l for early help and encouragement; Bette Hellinger for assistance in setting up the confer ence; and Mary Raines and Virginia Foster for considerable aid in the pre paration of papers and many other conference matters. The friendly advice of the late James Cornman was also importantly helpful. April,1979 GEORGE S. PAPPAS ix INTRODUCTION The papers in this volume deal in different ways with the related issues of epistemic justification or warrant, and the analysis of factual knowledge."

Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.

Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique multi-modality approach to management of all types of primary and secondary liver tumors. The biology of liver cancers, state of the art radiologic imaging and novel, non-surgical interventional strategies are given. There is an in depth analysis of surgical options including transplantation, resection, interstitial ablation techniques and liver-directed chemotherapy for hepatocellular carcinoma, bile duct cancers, and colorectal and neuroendocrine liver metastases. Because of the unique and comprehensive examination of liver tumors, this work is an excellent resource for surgical, transplant and medical oncologists, surgeons, gastroenterologists, and radiologists.

Dr. Michael G. Pappas has distilled in this remarkable, nearly 500-page ring-bound handbook over twenty years' experience as a research scientist at the bench, a senior manager wrestling with day-to-day business problems, and as a consultant providing critical expertise to small-to-medium size biotechnology firms and the federal government. The result is a gold mine of information about the industry and a solid foundation for starting and managing a new business in the biotechnology segment of the healthcare industry. On the business side, The BioBusiness Handbook illuminates how the individual parts of a company interact and work together and discusses in detail the stages and methods of product development, the secrets of quality control and assurance, how biotechnology products are marketed, the inside story on regulatory compliance, and navigating the new drug approval process.
On the science side of the business, Dr. Pappas devotes almost forty percent of the book to summarizing and explaining the emerging technologies that will dominate future developments in the next ten years, among them, advances in gene therapy, transgenesis, artificial tissues and organs, diagnostics, bioremediation, nucleic acid probe assays, the human genome initiative, and vaccine, drug, antisense, and third-strand therapies.
The BioBusiness Handbook contains over 1100 references to books, periodicals, and scientific journals (including 1994 references) that will round out your knowledge and make you an expert in the business of biotechnology. To receive a detailed brochure about this unique resource, please check the information box on the order form.

With one exception, all of the papers in this volume were originally presented at a conference held in April, 1978, at The Ohio State University. The excep tion is the paper by Wilfrid Sellars, which is a revised version of a paper he originally published in the Journal of Philosophy, 1973. However, the present version of Sellars' paper is so thoroughly changed from its original, that it is now virtually a new paper. None of the other nine papers has been published previously. The bibliography, prepared by Nancy Kelsik, is very extensive and it is tempting to think that it is complete. But I believe that virtual com pleteness is more likely to prove correct. The conference was made possible by grants from the College of Human ities and the Graduate School, Ohio State University, as well as by a grant from the Philosophy Department. On behalf of the contributors, I want to thank these institutions for their support. I also want to thank Marshall Swain and Robert Turnbu l for early help and encouragement; Bette Hellinger for assistance in setting up the confer ence; and Mary Raines and Virginia Foster for considerable aid in the pre paration of papers and many other conference matters. The friendly advice of the late James Cornman was also importantly helpful. April,1979 GEORGE S. PAPPAS ix INTRODUCTION The papers in this volume deal in different ways with the related issues of epistemic justification or warrant, and the analysis of factual knowledge."

This major version -- the first since 1982 -- features an extensive change in content, as well as a more capacious page and wider margins. While maintaining scrupulous examination of positions, arguments, and objections, every chapter has been reworked to improve its organisation, to make it more accessible and engaging to the student, and to reflect recent discussions. Chapter One introduces the student to the nature of philosophy as a discipline and to the methods of philosophical argument. Subsequent chapters treat the same fundamental topics as in earlier editions: knowledge and scepticism, freedom and determinism, the mind-body problem, the rationality of belief in God, and the problem of choosing an ethical standard. New exercises have been added throughout.

Within the field of infectious diseases, medical mycology has experienced significant growth over the last decade. Invasive fungal infections have been increasing in many patient populations, including: those with AIDS; transplant recipients; and the elderly. As these populations grow, so does the diversity of fungal pathogens. Paralleling this development, there have been recent launches of several new antifungal drugs and therapies. Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.

Even as so-called megachurches capture the attention of many church watchers, small congregations continue to dominate America s religious landscape in both rural and urban settings. Although sometimes obscured by their larger siblings, these small churches play a prominent role and hold a unique place in both local and national cultures. How can leaders help to keep these often at-risk churches alive and to meet their potential for ministry? Small-church expert Tony Pappas has gathered a cornucopia of essays into an indispensable book for anyone interested in the rich life of these small but significant congregations. Drawing on classic and updated articles by a variety of writers from his own small-church newsletter The Five Stones; from Alban journals Action Information and Congregations; and adding new pieces developed especially for this volume, Pappas provides timeless ideas on learning to value, pastor, develop, and lead the small church. In addition to time-honored articles by the editor, other contributors to this volume include Sherry and Douglas Alan Walrath, Gary Farley, Lawrence W. Farris, Loren Mead, Caroline Westerhoff, Steven Burt, Carl Dudley, David Ray, James Lowery, and a host of others known for their work-and love-for the small church. Readers of Inside the Small Church will come away with a renewed love and appreciation for these vital congregations as well as with new skills for ministry."

This demonstrates amazingly, with unflinching honesty and a wonderfully redeeming sense of humor, a resource especially helpful in motivating change and growth by mobilizing the natural strengths of small churches. For you who have been looking for a reliable guide to interpret the world of the small church, look no further since this provides all the insights you need. Includes images and models and strategies that reflect the profound uniqueness of the small church. It clearly shows leaders how to lead within the dynamics and culture of the small congregation. This is theologically sound and eminently practical. A must reading for anyone who is or plans to be a leader in a small church. Excellent for small roup study.