The introduction of the new acrylic bone cements Palamed and Copal is the reason for combining the recent knowledge of some of the experts in the field in this book. Palamed and Copal have been developed by the same people who made the well-known Palacos and Refobacine Palacos. Compared with Palacos, Palamed shows the same excellent mechanical properties and additionally improved handling characteristics. Copal is a new antibiotic-loaded bone cement especially designed for revision cases. This book presents comparative clinical and preclinical studies in classical and modern bone cements focusing on properties, techniques, antibiotic-loaded cements, and osteolysis.