|
Showing 1 - 5 of
5 matches in All Departments
Progress in biological and biochemical research is based mainly on
a better understanding of life processes. Controlled manipulation
of the structure of biological mac- romolecules and the synthesis
of biomimetic models are the basic tools used in bioorganic
chemistry. This new series, Bioorganic Chemistry Frontiers, will
bring to- gether critical reviews on the progress in this field.
It seems likely that no project of this magnitude is undertaken in
the absence of several motivations. This book is no exception.
There are, from our perspective, at least two rational reasons for
conducting this cataloging and organizational effort. The first of
these is the obvious fact that a very large number of macrocyclic
polyethers have now been prepared and nowhere is there a
comprehensive listing of them. A number of excellent reviews have
been published dealing with one or more aspects of macrocycle
chemistry, but we felt a great need for a single source listing
known compounds. We have, the- fore, attempted to provide such a
listing to assist ourselves in keeping track as well as, we hope,
helping others in this field. We also felt that there was a need
for a survey of methods which have been utilized in the syntheses
of these cation binders so that the novice could establish some
starting point. Wherever possible, we have also attempted to point
to the motivations which en gendered the various syntheses. The
somewhat irrational reason which propelled us into this endeavor
was the ques tioning of Charlie Morgan who often asked if one or
another obscure compound had been synthesized. As often as not, we
were uncertain arid now at least have a reference which, if not
absolutely complete, will at least save face."
Part of a series which presents reports of efforts in all areas of
supramolecular science, this volume discusses a variety of topics
in the field.
In this volume, inorganic, organic, and bioorganic chemistry are
represented in contributions from around the world. Pioneering work
in self-assembled structures organized by the use of transition
metals is described in chapter 1, followed by details of extensive
studies of self-assembled structures formed from various
biomolecules in chapter 2. The next two chapters describe the
formation of spherical molecular containers and their understanding
of such structures based on Platonic and Archimedean solids, and
the fascinating family of synthetic peptide receptors and the
interactions that can be explored using these host molecules. In
chapter 5 a mixture of computational chemistry, drug design, and
synthetic organic and inorganic chemistry in the development of
superoxide dismutase mimics is described. The final two chapters
discuss the bioorganic and supramolecular principles required for
the design of synthetic artificial enzymes, and the supramolecular
self-assembly and its possible role in the origin of life.
It is hoped that this broad, international view of supramolecular
chemistry and the many directions it leads will be of interest to
those already in the field. It is also hoped that those outside the
field may see extensions of their own work that will bring them
into it.
This volume presents a variety of articles that encompass the broad
scope of supramolecular chemistry. Reusch's chapter covers
biological channel compounds, while the work of Hall and Kirkovits
looks into their synthetic counterparts. Metal ion sensors,
calixarenes and "crystal engineering" are described by pioneers in
these fields. This work, whilst current and authoritative, shows us
that much remains to be undertaken and understood. It is hoped that
this volume will be of interest to those who wish to fill these
gaps; scientists already in the field and those who may see
extensions of their own work that will bring them into it.
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
Hampstead
Diane Keaton, Brendan Gleeson, …
DVD
R66
Discovery Miles 660
|