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This reference handbook is the first to provide a comprehensive
overview, systematically characterizing all known transporters
involved in drug elimination and resistance. Combining recent
knowledge on all known classes of drug carriers, from microbes to
man, it begins with a look at human and mammalian transporters.
This is followed by microbial, fungal and parasitic transporters
with special attention given to transport across those
physiological barriers relevant for drug uptake, distribution and
excretion.
As a result, this key resource lays the foundations for
understanding and investigating the molecular mechanisms for
multidrug resistance in cancer cells, microbial resistance to
antibiotics and pharmacokinetics in general.
For anyone working with antibiotics and cancer chemotherapeutics,
as well as being of prime interest to biochemists and
biophysicists.
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