This book highlights the different aspects of the research project “E4C Horizon 2020 European Project” aimed at fighting the coronavirus by combining the best supercomputing resources and artificial intelligence with state-of-the-art experimental facilities up through clinical validation. Coronavirus disease has become an important public issue across the globe since December 2019. There is an urgent need to develop potent anti-COVID-19 agents for the prevention of the outbreak and stop viral infections. To this aim, a public–private consortium composed by European and national infrastructures, center of excellence, universities, and a pharmaceutical company started the E4C Horizon 2020 European Project: Its core idea was to use the EXaSCale smArt pLatform Against paThogEns (EXSCALATE) supercomputing platform for a process known as “drug repurposing”, namely to identify the most promising safe in man drugs for immediate treatment of the already infected population and then novel pan-coronavirus inhibitors to address future emergencies. This ambitious goal exploited a “chemical library” of 500 billion molecules, thanks to a processing capacity of more than 3 million molecules per second, made available by the computing power of the EXSCALATE platform.

This book is the first to provide a comprehensive, readily understandable report on the European Space Agency's Gaia mission that will meet the needs of a general audience. It takes the reader on an exciting journey of discovery, explaining how such a scientific satellite is made, presenting the scientific results available from Gaia to date, and examining how the collected data will be used and their likely scientific consequences. The Gaia mission will provide a complete and high-precision map of the positions, distances, and motions of the stars in our galaxy. It will revolutionize our knowledge on the origin and evolution of the Milky Way, on the effects of mysterious dark matter, and on the birth and evolution of stars and extrasolar planets. The Gaia satellite was launched in December 2013 and has a foreseen operational lifetime of five to six years, culminating in a final stellar catalogue in the early 2020s. This book will appeal to all who have an interest in the mission and the profound impact that it will have on astronomy.

Taking inspiration from Siv Cedering's poem in the form of a fictional letter from Caroline Herschel that refers to "my long, lost sisters, forgotten in the books that record our science", this book tells the lives of twenty-five female scientists, with specific attention to astronomers and mathematicians. Each of the presented biographies is organized as a kind of "personal file" which sets the biographee's life in its historical context, documents her main works, highlights some curious facts, and records citations about her. The selected figures are among the most representative of this neglected world, including such luminaries as Hypatia of Alexandra, Hildegard of Bingen, Elisabetha Hevelius, and Maria Gaetana Agnesi. They span a period of about 4000 years, from En HeduAnna, the Akkadian princess, who was one of the first recognized female astronomers, to the dawn of the era of modern astronomy with Caroline Herschel and Mary Somerville. The book will be of interest to all who wish to learn more about the women from antiquity to the nineteenth century who played such key roles in the history of astronomy and science despite living and working in largely male-dominated worlds.