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Development of cancer, a dreadful disease of mankind, is a
multi-stage process involving numerous molecular alterations at
both genomic and proteomic levels. Immense research for the past
several decades in the field of cancer identified many such
mutations and their role in carcinogenesis. Concept of 'fusion
genes' seeded way back in 20th century has now grown into a new
field of cancer research. However, there is a lack of knowledge
among scientists about these fusion genes and their importance in
cancer, which can be mainly attributed to unavailability of a
comprehensive book on this topic. Therefore, this book is first of
its kind and aims at giving a detailed idea on the formation of
gene fusions and their importance in the development and
progression of cancer; techniques to identify novel gene fusions;
and therapeutics available to target various fusion proteins and
their impact in cancer therapy by compiling the information from
the literature available till date.
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