Bioinformatics has never been as popular as it is today. The genomics revolution is generating so much data in such rapid succession that it has become difficult for biologists to decipher. In particular, there are many problems in biology that are too large to solve with standard methods. Researchers in evolutionary computation (EC) have turned their attention to these problems. They understand the power of EC to rapidly search very large and complex spaces and return reasonable solutions. While these researchers are increasingly interested in problems from the biological sciences, EC and its problem-solving capabilities are generally not yet understood or applied in the biology community.

This book offers a definitive resource to bridge the computer science and biology communities. Gary Fogel and David Corne, well-known representatives of these fields, introduce biology and bioinformatics to computer scientists, and evolutionary computation to biologists and computer scientists unfamiliar with these techniques. The fourteen chapters that follow are written by leading computer scientists and biologists who examine successful applications of evolutionary computation to various problems in the biological sciences.
* Describes applications of EC to bioinformatics in a wide variety of areas including DNA sequencing, protein folding, gene and protein classification, drug targeting, drug design, data mining of biological databases, and biodata visualization.
* Offers industrial and academic researchers in computer science, biology, and bioinformatics an important resource for applying evolutionary computation.
* Includes a detailed appendix of biological data resources.

The Wright brothers have long received the lion's share of credit for inventing the airplane. But a California scientist succeeded in flying gliders twenty years before the Wright's powered flights at Kitty Hawk in 1903. Quest for Flight reveals the amazing accomplishments of John J. Montgomery, a prolific inventor who piloted the glider he designed in 1883 in the first controlled flights of a heavier-than-air craft in the Western Hemisphere.Re-examining the history of American aviation, Craig S. Harwood and Gary B. Fogel present the story of human efforts to take to the skies. They show that history's nearly exclusive focus on two brothers resulted from a lengthy public campaign the Wrights waged to profit from their aeroplane patent and create a monopoly in aviation. Countering the aspersions cast on Montgomery and his work, Harwood and Fogel build a solidly documented case for Montgomery's pioneering role in aeronautical innovation. As a scientist researching the laws of flight, Montgomery invented basic methods of aircraft control and stability, refined his theories in aerodynamics over decades of research, and brought widespread attention to aviation by staging public demonstrations of his gliders. After his first flights near San Diego in the 1880s, his pursuit continued through a series of glider designs. These experiments culminated in 1905 with controlled flights in Northern California using tandem-wing Montgomery gliders launched from balloons. These flights reached the highest altitudes yet attained, demonstrated the effectiveness of Montgomery's designs, and helped change society's attitude toward what was considered ""the impossible art"" of aerial navigation. Inventors and aviators working west of the Mississippi at the turn of the twentieth century have not received the recognition they deserve. Harwood and Fogel place Montgomery's story and his exploits in the broader context of western aviation and science, shedding new light on the reasons that California was the epicenter of the American aviation industry from the very beginning.