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Showing 1 - 25 of
647 matches in All Departments
The Human Mitochondrial Genome: From Basic Biology to Disease
offers a comprehensive, up-to-date examination of human
mitochondrial genomics, connecting basic research to translational
medicine across a range of disease types. Here, international
experts discuss the essential biology of human mitochondrial DNA
(mtDNA), including its maintenance, repair, segregation, and
heredity. Furthermore, mtDNA evolution and exploitation, mutations,
methods, and models for functional studies of mtDNA are dealt with.
Disease discussion is accompanied by approaches for treatment
strategies, with disease areas discussed including cancer,
neurodegenerative, age-related, mtDNA depletion, deletion, and
point mutation diseases. Nucleosides supplementation, mitoTALENs,
and mitoZNF nucleases are among the therapeutic approaches examined
in-depth. With increasing funding for mtDNA studies, many
clinicians and clinician scientists are turning their attention to
mtDNA disease association. This book provides the tools and
background knowledge required to perform new, impactful research in
this exciting space, from distinguishing a haplogroup-defining
variant or disease-related mutation to exploring emerging
therapeutic pathways.
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The Lost Patrol (DVD)
Thogun, Ivo Canelas, Daniel de Oliveira, Sergio Rubini, Francisco Gaspar, …
2
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R98
Discovery Miles 980
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Ships in 10 - 25 working days
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Vicente Ferraz directs this war drama based on real events of World
War II. Set during the winter of 1944, a Brazilian Expeditionary
Force on a minesweeping patrol in Italy find themselves lost in a
land far from their base in the mountains. As they embark on an
horrific journey back to camp they come across two army deserters;
one Italian and one German. Forming an unlikely group of renegades
the men set about crossing the infamous Road 47 to achieve safe
passage to their futures.
This book brings together works by specialists from various areas
of the social sciences to reflect on the presence of China in
Portugal and in Portuguese-speaking territories. From the first
Chinese coolies that migrated to the former Portuguese colonies
more than 100 years ago, to the current investments along the Belt
and Road Initiative, we take the pulse of this historic, social,
political and economic presence and flows, that continues to renew
and reinvent itself in the face of the challenges of
contemporaneity.
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