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Apoptosis (Paperback)
Ghatage Dipak, Gosavi Suchitra, Ganvir Sindhu
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R1,064
Discovery Miles 10 640
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Ships in 10 - 15 working days
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Apoptosis (Programmed Cell death) is one of the essential
processes. Balance between cell division and cell death is of
utmost importance for the development and maintenance of
multi-cellular organism. Disorders of either process have
pathologic consequences and can lead to disturbed embryogenesis,
neuro-degerative diseases, or the development of cancers. This book
reviews the apoptotic as well as anti-apoptotic molecules along
with molecular pathways, which may alter in many diseases. The
elucidations of the molecular mechanisms of apoptosis and their
correlation with a vast array of human diseases have generated
optimism for implementation of this knowledge for treatment
purposes.
A cell is a membrane bound structure containing biomolecules, such
as nucleic acids, proteins, and polysaccharides. The Endoplasmic
Reticulum is organized into a netlike labyrinth of branching
tubules and flattened sacs extending throughout the cytosol.The ER
has a central role in lipid and protein biosynthesis.The ER
membrane makes a major contribution to mitochondrial and
peroxisomal membranes by producing most of their lipids. The
endoplasmic reticulum (ER) has many different functions. These
include the translocation of proteins (such as secretory proteins)
across the ER membrane; the integration of proteins into the
membrane; the folding and modification of proteins in the ER lumen;
the synthesis of phospholipids and steroids on the cytosolic side
of the ER membrane; and the storage of calcium ions in the ER lumen
and their regulated release into the cytosol.
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