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An up-to-date comprehensive overview of the GABA B receptor system
with a particular focus on the most recent therapeutic applications
and potential. This receptor system has recently been implicated in
several diseases and disorders including gastroesophageal reflux
disease, epilepsy, mood disorders, depression, and alcohol and
substance use disorder. The authors, leading researchers in the
field, explore a number of approaches, including medicinal
chemistry, molecular biology, physiology, and preclinical and
clinical pharmacology. This overview provides a translational
perspective on the potential of the GABA B receptor pharmacology.
An up-to-date comprehensive overview of the GABA B receptor system
with a particular focus on the most recent therapeutic applications
and potential. This receptor system has recently been implicated in
several diseases and disorders including gastroesophageal reflux
disease, epilepsy, mood disorders, depression, and alcohol and
substance use disorder. The authors, leading researchers in the
field, explore a number of approaches, including medicinal
chemistry, molecular biology, physiology, and preclinical and
clinical pharmacology. This overview provides a translational
perspective on the potential of the GABA B receptor pharmacology.
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