Recent progress in fundamental tumor immunology has lead to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immuntiy with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens capable of eliciting immune responses has now resulted in the development of antigen-specific immunotherapy strategies. Vaccination with defined peptide epitopes, purified proteins, cell components and whole cells expressing defined tumor antigens provides for the first time an opportunity to measure antigen-specific immune responses in vaccinated patients, and to correlate immunity with clinical outcome.
Tumor Antigens Recognized by T Cells and Antibodies provides a comprehensive overview of the molecular nature of tumor antigens that can be recognised by antibodies, helper T lymphocytes and cytotoxic T lymphocytes. Novel strategies to enhance ineffective immunity against such antigens provide the basis for improved immunotherapy protocols for patient treatment. With contributions from a host of international experts in the field, this book provides invaluable information for clinicians and researchers with an interest in cancer immunotherapy.

eBook available with sample pages: 0203217659

Recent advances in basic immunology and molecular biology have resulted in new immunologically based therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation and interplay of cells involved in antitumor immunity have made the clinical control of some cancers using biological reagents more plausible than previously thought.
An invaluable source for clinicians, researchers and students, Tumor Immunology presents an introductory overview of the immunology of cancer including therapeutic approaches. Topics covered include the immune recognition of cancer-tumor antigens, humoral recognition of cancer and the immunotherapy of cancer.

eBook available with sample pages: 0203301854

Recent advances in immunology and molecular biology have resulted in new therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation, and interplay of cells involved in anti-tumor immunity have made the clinical control of some cancers more plausible than previously thought. An invaluable source for clinicians, researchers, and students, Tumor Immunology presents an introductory overview of the immunology of cancer including therapeutic approaches. Topics covered include the immune recognition of cancer-tumor antigens, humoral recognition of cancer, and the immunotherapy of cancer.