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Showing 1 - 4 of 4 matches in All Departments
In Silico Chemistry and Biology: Current and Future Prospects provides a compact overview on recent advances in this highly dynamic branch of chemistry. Various methods of protein modelling and computer-assisted drug design are presented, including fragment- and ligand-based approaches. Many successful practical applications of these techniques are demonstrated. The authors also look to the future and describe the main challenges of the field.
Medical Microbiology is an excellent and easy-to-use textbook which explains the roles of microorganisms in human health and illness. Written in a clear and engaging manner, the book provides an overview of pathogenic organisms, their diagnosis and treatment tools as well as the molecular mechanisms of hostpathogen interactions and antimicrobial drug resistance.
Chemical Drug Design provides a compact overview on recent advances in this rapidly developing field. With contributions on in silico drug design, natural product based compounds, as well as on ligand- and structure-based approaches, the authors present innovative methods and techniques for identifying and synthetically designing novel drugs.
Soybean rust and yellow mosaic diseases substantially reduce the yield. A Disease resistant variety developed by transfer of resistance genes in superior line is the most desirable approach. Field screening revealed significant differences among genotypes for disease reaction. Under field evaluation, none of the genotypes including rust differentials (PI 200492, PI 230970, PI 462312, 'Ankur', PI 459025, PI 200477, PI 230971, PI 459024, TK - 5 and Wayne) showed rust resistance, indicating evolution of new rust race(s); However, yellow mosaic (YMV) resistant varieties 'PK 416', 'PK 564', 'PK 1024', 'PK 1029', 'SL 528' have still maintained their resistance status. The genotypes SL 603, SL 295 remained free of YMV, while SL 328 and three derived lines from the cross PS 1024 x Ankur (F3) were highly resistant. F2 lines derived from crosses PS 1024 x Ankur, Ankur x PS 1024 and PK 416 x Samrat and genotypes Ankur, PS 1024, PS 1029, PK 416 and PS 564 were resistant. This work caters to the plant breeders and pathologist, working on the host-pathogen interactions with information on hybridization, field screening and development of disease tolerant varieties.
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