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Glial Neuronal Signaling fills a need for a monograph/textbook to
be used in advanced courses or graduate seminars aimed at exploring
glial-neuronal interactions. Even experts in the field will find
useful the authoritative summaries of evidence on ion channels and
transporters in glia, genes involved in signaling during
development, metabolic cross talk and cooperation between
astrocytes and neurons, to mention but a few of the timely
summaries of a wide range of glial-neuronal interactions. The
chapters are written by the top researchers in the field of
glial-neuronal signaling, and cover the most current advances in
this field. The book will also be of value to the workers in the
field of cell biology in general. When we think about the brain we
usually think about neurons. Although there are 100 billion neurons
in mammalian brain, these cells do not constitute a majority. Quite
the contrary, glial cells and other non-neuronal cells are 10-50
times more numerous than neurons. This book is meant to integrate
the emerging body of information that has been accumulating,
revealing the interactive nature of the brain's two major neural
cell types, neurons and glia, in brain function.
Glial Neuronal Signaling fills a need for a monograph/textbook to
be used in advanced courses or graduate seminars aimed at exploring
glial-neuronal interactions. Even experts in the field will find
useful the authoritative summaries of evidence on ion channels and
transporters in glia, genes involved in signaling during
development, metabolic cross talk and cooperation between
astrocytes and neurons, to mention but a few of the timely
summaries of a wide range of glial-neuronal interactions. The
chapters are written by the top researchers in the field of
glial-neuronal signaling, and cover the most current advances in
this field. The book will also be of value to the workers in the
field of cell biology in general. Illustrations included in the
accompanying CD are suitable for professional presentations and
instructional materials by researchers, physicians, teachers and
members of the pharmaceutical industry. When we think about the
brain we usually think about neurons. Although there are 100
billion neurons in mammalian brain, these cells do not constitute a
majority. Quite the contrary, glial cells and other non-neuronal
cells are 10-50 times more numerous than neurons. This book is
meant to integrate the emerging body of information that has been
accumulating, revealing the interactive nature of the brain's two
major neural cell types, neurons and glia, in brain function. The
text is supported by the CD containing all pictures, including
color, tables and movies.
In mammals the glial (or glue) cells contribute some 50% of the
volume of the brain. In contrast to the traditional view that they
have a purely physically supportive role, research in the last
three decades has shown that glia interact morphologically,
biochemically and physiologically with neurons during changes in
behaviour. The evidence suggests that glia may modulate neuronal
activity and thereby influence behaviour. This 1998 book was the
first to describe and discuss these neuronal-glial interactions in
relation to behaviour. A distinguished set of authors discuss these
interactions from a number of viewpoints, and the book will
familiarise neuroscientists, zoologists, physiologists and
psychologists with the new knowledge of how neurons and glial cells
interact with each other to affect behaviour.
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