Digital development not only marked today's world in terms of technology, but also transformed our social life into different forms, and it has moved our social practices to a different media.With the development of technology, one of the many aspects of the digital representation that penetrates all areas of life is created by new technology's impacts on human health and behavior. Digital technology that penetrates all areas of life has some impacts on human health and behavior. Some of them are due to virtual reality, and some are due to overuse of new media. These include the following diseases such as cyber disease, digital addiction, binge watching, ego surfing, and many more. The book tackles the abovementioned diseases specifically and includes a wide spectrum of both literature reviews and original studies regarding the diseases of the digital era for a better comprehension of today's world. The studies help to deal with these diseases and develop defense mechanisms against them.