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Showing 1 - 19 of 19 matches in All Departments

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds (Paperback): Goutam Brahmachari Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds (Paperback)
Goutam Brahmachari
R1,522 Discovery Miles 15 220 Ships in 12 - 17 working days

Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure-activity relationships.

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds (Hardcover, New): Goutam Brahmachari Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds (Hardcover, New)
Goutam Brahmachari
R5,691 Discovery Miles 56 910 Ships in 12 - 17 working days

Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure-activity relationships.

Biotechnology of Microbial Enzymes - Production, Biocatalysis, and Industrial Applications (Paperback, 2nd edition): Goutam... Biotechnology of Microbial Enzymes - Production, Biocatalysis, and Industrial Applications (Paperback, 2nd edition)
Goutam Brahmachari
R3,615 Discovery Miles 36 150 Ships in 12 - 17 working days

Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications, Second Edition provides a complete survey of the latest innovations on microbial enzymes, highlighting biotechnological advances in their production and purification along with information on successful applications as biocatalysts in several chemical and industrial processes under mild and green conditions. The application of recombinant DNA technology within industrial fermentation and the production of enzymes over the last three decades have produced a host of useful chemical and biochemical substances. The power of these technologies results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology, all of which is covered insightfully and in-depth within the book. This fully revised, second edition is updated to address the latest research developments and applications in the field, from microbial enzymes recently applied in drug discovery to penicillin biosynthetic enzymes and penicillin acylase, xylose reductase, and microbial enzymes used in antitubercular drug design. Across the chapters, the use of microbial enzymes in sustainable development and production processes is fully considered, with recent successes and ongoing challenges highlighted.

Discovery and Development of Neuroprotective Agents from Natural Products (Paperback): Goutam Brahmachari Discovery and Development of Neuroprotective Agents from Natural Products (Paperback)
Goutam Brahmachari
R4,753 R4,291 Discovery Miles 42 910 Save R462 (10%) Ships in 12 - 17 working days

Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer's disease, Parkinson's disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs.

Green Synthetic Approaches for Biologically Relevant Heterocycles (Hardcover): Goutam Brahmachari Green Synthetic Approaches for Biologically Relevant Heterocycles (Hardcover)
Goutam Brahmachari
R5,431 Discovery Miles 54 310 Ships in 12 - 17 working days

Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry.

Discovery and Development of Anti-Breast Cancer Agents from Natural Products (Paperback): Goutam Brahmachari Discovery and Development of Anti-Breast Cancer Agents from Natural Products (Paperback)
Goutam Brahmachari
R4,579 Discovery Miles 45 790 Ships in 12 - 17 working days

Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields. Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area.

Green Synthetic Approaches for Biologically Relevant Heterocycles - Volume 1: Advanced Synthetic Techniques (Paperback, 2nd... Green Synthetic Approaches for Biologically Relevant Heterocycles - Volume 1: Advanced Synthetic Techniques (Paperback, 2nd edition)
Goutam Brahmachari
R5,355 Discovery Miles 53 550 Ships in 12 - 17 working days

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.

Organophosphorus Chemistry - Novel Developments (Hardcover): Gyoergy Keglevich Organophosphorus Chemistry - Novel Developments (Hardcover)
Gyoergy Keglevich; Contributions by Peter Abranyi-Balogh, Peter Bagi, Erika Balint, Bubun Banerjee, …
R4,705 Discovery Miles 47 050 Ships in 10 - 15 working days

Organophosphorus Chemistry presents a groundbreaking resource in this branch of organic chemistry that demonstrates how phosphorus-containing compounds can be manipulated in a variety of organic reactions. The authors give an overview of the newest trends and synthesis strategies, introduce bioactive and environmentally friendly organophosphorus compounds and show their importance in mainstream organic chemistry.

Biotechnology of Microbial Enzymes - Production, Biocatalysis and Industrial Applications (Paperback): Goutam Brahmachari,... Biotechnology of Microbial Enzymes - Production, Biocatalysis and Industrial Applications (Paperback)
Goutam Brahmachari, Arnold L. Demain, Jose L Adrio
R3,006 Discovery Miles 30 060 Ships in 12 - 17 working days

Biotechnology of Microbial Enzymes: Production, Biocatalysis and Industrial Applications provides a complete survey of the latest innovations on microbial enzymes, highlighting biotechnological advances in their production and purification along with information on successful applications as biocatalysts in several chemical and industrial processes under mild and green conditions. Applications of microbial enzymes in food, feed, and pharmaceutical industries are given particular emphasis. The application of recombinant DNA technology within industrial fermentation and the production of enzymes over the last 20 years have produced a host of useful chemical and biochemical substances. The power of these technologies results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology, all of which is covered insightfully and in-depth within the book.

Discovery and Development of Antidiabetic Agents from Natural Products - Natural Product Drug Discovery (Paperback): Goutam... Discovery and Development of Antidiabetic Agents from Natural Products - Natural Product Drug Discovery (Paperback)
Goutam Brahmachari
R4,102 R3,712 Discovery Miles 37 120 Save R390 (10%) Ships in 12 - 17 working days

Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications. Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics.

Discovery and Development of Anti-inflammatory Agents from Natural Products (Paperback): Goutam Brahmachari Discovery and Development of Anti-inflammatory Agents from Natural Products (Paperback)
Goutam Brahmachari
R4,532 Discovery Miles 45 320 Ships in 12 - 17 working days

Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products. Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases.

Total Synthesis of Bioactive Natural Products (Paperback): Goutam Brahmachari Total Synthesis of Bioactive Natural Products (Paperback)
Goutam Brahmachari
R4,591 R4,145 Discovery Miles 41 450 Save R446 (10%) Ships in 12 - 17 working days

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products.

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases (Paperback): Goutam... Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases (Paperback)
Goutam Brahmachari
R5,044 R4,601 Discovery Miles 46 010 Save R443 (9%) Ships in 12 - 17 working days

Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.

Room Temperature Organic Synthesis (Hardcover): Goutam Brahmachari Room Temperature Organic Synthesis (Hardcover)
Goutam Brahmachari
R3,525 R2,829 Discovery Miles 28 290 Save R696 (20%) Ships in 12 - 17 working days

Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry.

Green Synthetic Approaches for Biologically Relevant Heterocycles - Volume 2: Green Catalytic Systems and Solvents (Paperback,... Green Synthetic Approaches for Biologically Relevant Heterocycles - Volume 2: Green Catalytic Systems and Solvents (Paperback, 2nd edition)
Goutam Brahmachari
R5,377 Discovery Miles 53 770 Ships in 12 - 17 working days

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.

Spectroscopic Properties Of Natural Flavonoids (Hardcover): Goutam Brahmachari Spectroscopic Properties Of Natural Flavonoids (Hardcover)
Goutam Brahmachari
R3,684 Discovery Miles 36 840 Ships in 10 - 15 working days

This book offers physical characteristics and spectral data of 150 selected natural compounds arranged according to their chemical structures in various sub-classes. These include natural source, molecular formula, chemical structure, physical characteristics (melting point, molecular weight, and specific rotation) and detailed spectral data (UV, FT-IR, 1H-NMR, 13C-NMR, 2D-NMR, Mass) along with their assignments for each compound.

Cardioprotective Natural Products: Promises And Hopes (Hardcover): Goutam Brahmachari Cardioprotective Natural Products: Promises And Hopes (Hardcover)
Goutam Brahmachari
R3,430 Discovery Miles 34 300 Ships in 10 - 15 working days

Cardioprotective Natural Products: Promises and Hopes focuses on the recent advances in the research of bioactive natural products with cardioprotective potential against various cardiovascular diseases/disorders. The aim of this book is to underline the promise and future hope in bioactive natural molecules, herbal formulations, natural dietary supplements and related materials in the prevention and cure of cardiovascular diseases in a scientific way.This book, which comprises a variety of about 9 chapters written by active researchers and leading experts, brings together an overview of current discoveries and trends in this field. This volume is also an outstanding source of information with regard to the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach adopted in this book ensures that it is much more interesting to scientists deeply engaged in the research and/or use of bioactive natural products. It will serve not only as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to prevent and treat disease manifestations, but will hopefully also motivate young scientists to engage in the dynamic field of natural products research.

Natural Bioactive Molecules - Impacts and Prospects (Hardcover): Goutam Brahmachari Natural Bioactive Molecules - Impacts and Prospects (Hardcover)
Goutam Brahmachari
R3,032 Discovery Miles 30 320 Ships in 12 - 17 working days

NATURAL BIOACTIVE MOLECULES: Impacts and Prospects in Medicinal Chemistry is an endeavor to underline how natural product research continues to make significant contributions in the domain of discovery and development of new medicinal entities. Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. Bioactive natural products are proving to be a rich source of novel therapeutics. Search for bioactive molecules from nature (plants, animals, microflora) continues to play an important role in fashioning new medicinal agents. With the advent of modern techniques, very particularly the rapid improvements in spectroscopic as well as accompanying advances in high-throughput screening techniques, it has become possible to have an enormous repository of bioactive natural compounds, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.This book, which will comprise a variety of at least fifteen chapters written by active researchers and leading experts in natural products chemistry on biologically active natural products, brings together an overview of current discoveries and trends in this remarkable field. This definite volume is also an outstanding source of information with regard to the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach dealt in this book would surely make the work much interesting to the scientists deeply engaged in the research and/or use of bioactive natural products. It will serve not only as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations, but also motivates young scientists to the dynamic field of bioactive natural products research.

Bioactive Natural Products: Opportunities And Challenges In Medicinal Chemistry (Hardcover): Goutam Brahmachari Bioactive Natural Products: Opportunities And Challenges In Medicinal Chemistry (Hardcover)
Goutam Brahmachari
R6,729 Discovery Miles 67 290 Ships in 10 - 15 working days

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

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