This book constitutes the refereed proceedings of the Second International Workshop on Spatio-temporal Image Analysis for Longitudinal and Time-Series Image Data, STIA 2012, held in conjunction with MICCAI 2012 in Nice, France, in October 2012. The 13 papers presented in this volume were carefully reviewed and selected from 22 submissions. They are organized in topical sections named: longitudinal registration and transport; spatio-temporal analysis for shapes; spatio-temporal analysis under appearance changes; and spatio-temporal analysis for biology.

This book constitutes the thoroughly refereed post-conference proceedings of the Third International Workshop on Spatio-temporal Image Analysis for Longitudinal and Time-Series Image Data, STIA 2014, held in conjunction with MICCAI 2014 in Boston, MA, USA, in September 2014. The 7 papers presented in this volume were carefully reviewed and selected from 15 submissions. They are organized in topical sections named: longitudinal registration and shape modeling, longitudinal modeling, reconstruction from longitudinal data, and 4D image processing.

The 8th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2005, was held in Palm Springs, California, USA, at the Riviera Resort, October 26-29, 2005. MICCAIhasbecomeapremierinternationalconferencewithin-depthpapers on the multidisciplinary ?elds of medical image computing, computer-assisted interventionandmedicalrobotics. Theconferencebringstogetherclinicians, b- logicalscientists, computer scientists, engineers, physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 632 full submissions (8 pages in length), an increase of 22% from 2004, from 36 di?erent countries and 5 continents (see ?g. 2). Based on a decision of the MICCAI board, this year's conference employed a double-blind review procedure on a trial basis. Our Program Committee was made up of 11 area chairs, each of whom supervised the review of almost 60 papers. Four reviews were generated for each paper from 262 reviewers and the area chairs. A ?nal paper selection meeting took place during two days in early June 2005 in Chapel Hill, North Carolina. We are especially grateful to Elizabeth Bullitt, Polina Golland, David Haynor, Rasmus Larsen, Greg Hager and Daniel Ruc ] kert, who attended this meetingandhelpedusmakethe?nalselections. MartinStynerprovidedvaluable help with information management and the Web-site, and James Stewart is acknowledgedforreliableandtimelysupportoftheWeb-basedreviewingsystem. Wearegratefultoeveryonewhoparticipatedinthe reviewprocess;theydonated a large amount of time and e?ort to make these volumes possible and insure a highlevelofquality."