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Triazenes: Synthesis and Chemical Properties.- Mechanisms of the
Biological Actions of Triazenes.- Triazenes and Triazene N-Oxides:
Antitumour Action in Animal Tumour Systems.- Antimestastatic Action
of Triazene Derivatives.- Effects of Triazenes on Immune
Responses.- Xenogenization of Experimental Tumors by Triazene
Derivatives.- The Metabolism of Antineoplastic Triazenes.- Notes on
the Metabolism, Pharmacokinetics and Mode of Action of N-Methyl and
N-Ethyl-Triazenes in Relation to Their Pharmacological Activity.-
Clinical Use of Triazenes.- Clinical Studies with the
p-Carboxyl-Dimethyl-Phenyl-Triazene CB10-277.- Triazenes:
Therapeutic Considerations and Perspectives.- Antitumor
Imidazotetrazines: Prodrugs Targeted to the Major Groove of DNA.-
O6-Alkylguanine-DNA-Alkyltransferase Gene Expression and the
Cytotoxicity of Triazenes.- N-Methylmelamines, a Unique Class of
Anti-Tumour Agents?.- Experimental Background and Early Clinical
Studies with Imidazotetrazine Derivatives.-
'O6-Alkylguanine-DNA-Alkyltransferase: Significance, Methods of
Measurement and Some Human Tumor and Normal Tissue Levels'
(Contributions of the Workshop).- Summary of Poster-Sessions.-
Contributors.
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