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Targeting Protein-Protein Interactions by Small Molecules (Hardcover, 1st ed. 2018): Chunquan Sheng, Gunda I. Georg Targeting Protein-Protein Interactions by Small Molecules (Hardcover, 1st ed. 2018)
Chunquan Sheng, Gunda I. Georg
R4,594 Discovery Miles 45 940 Ships in 12 - 19 working days

This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.

Targeting Protein-Protein Interactions by Small Molecules (Paperback, Softcover reprint of the original 1st ed. 2018): Chunquan... Targeting Protein-Protein Interactions by Small Molecules (Paperback, Softcover reprint of the original 1st ed. 2018)
Chunquan Sheng, Gunda I. Georg
R2,888 Discovery Miles 28 880 Ships in 10 - 15 working days

This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.

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