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This book highlights recent advances in and diverse techniques for
exploring the plasma membrane's structure and function. It starts
with two chapters reviewing the history of membrane research and
listing recent advances regarding membrane structure, such as the
semi-mosaic model for red blood cell membranes and the protein
layer-lipid-protein island model for nucleated tissue cell
membranes. It subsequently focuses on the localization and
interactions of membrane components, dynamic processes of membrane
transport and transmembrane signal transduction. Classic and
cutting-edge techniques (e.g. high-resolution atomic force
microscopy and super-resolution fluorescence microscopy) used in
biophysics and chemistry are presented in a very comprehensive
manner, making them useful and accessible to both researchers in
the field and novices studying cell membranes. This book provides
readers a deeper understanding of the plasma membrane's
organization at the single molecule level and opens a new way to
reveal the relationship between the membrane's structure and
functions, making it essential reading for researchers in various
fields.
Chemical Theory and Multiscale Simulation in Biomolecules: From
Principles to Case Studies helps readers understand what simulation
is, what information modeling of biomolecules can provide, and how
to compare this information with experiments. Beginning with an
introduction to computational theory for modeling, the book goes on
to describe how to control the conditions of modeling systems and
possible strategies for time-cost savings in computation. Part Two
further outlines key methods, with step-by-step guidance supporting
readers in studying and practicing simulation processes. Part Three
then shows how these theories are controlled and applied in
practice, through examples and case studies on varied applications.
This book is a practical guide for new learners, supporting them in
learning and applying molecular modeling in practice, whilst also
providing more experienced readers with the knowledge needed to
gain a deep understanding of the theoretical background behind key
methods.
This book highlights recent advances in and diverse techniques for
exploring the plasma membrane's structure and function. It starts
with two chapters reviewing the history of membrane research and
listing recent advances regarding membrane structure, such as the
semi-mosaic model for red blood cell membranes and the protein
layer-lipid-protein island model for nucleated tissue cell
membranes. It subsequently focuses on the localization and
interactions of membrane components, dynamic processes of membrane
transport and transmembrane signal transduction. Classic and
cutting-edge techniques (e.g. high-resolution atomic force
microscopy and super-resolution fluorescence microscopy) used in
biophysics and chemistry are presented in a very comprehensive
manner, making them useful and accessible to both researchers in
the field and novices studying cell membranes. This book provides
readers a deeper understanding of the plasma membrane's
organization at the single molecule level and opens a new way to
reveal the relationship between the membrane's structure and
functions, making it essential reading for researchers in various
fields.
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