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Since the discovery of X-rays and radioactivity, ionizing
radiations have been widely applied in medicine both for diagnostic
and therapeutic purposes. The risks associated with radiation
exposure and handling led to the parallel development of the field
of radiation protection.
Pioneering experiments done by Sanche and co-workers in 2000 showed
that low-energy secondary electrons, which are abundantly generated
along radiation tracks, are primarily responsible for radiation
damage through successive interactions with the molecular
constituents of the medium. Apart from ionizing processes, which
are usually related to radiation damage, below the ionization level
low-energy electrons can induce molecular fragmentation via
dissociative processes such as internal excitation and electron
attachment. This prompted collaborative projects between different
research groups from European countries together with other
specialists from Canada, the USA and Australia.
This booksummarizes the advances achieved by these research groups
after more than ten years of studies on radiation damage in
biomolecular systems.
An extensive Part I deals with recent experimental and
theoretical findings on radiation induced damage at the molecular
level. It includes many contributions on electron and
positroncollisions with biologically relevant molecules. X-ray and
ion interactions are also covered. Part II addresses different
approaches to radiation damage modelling. In Part III biomedical
aspects of radiation effects are treated on different scales. After
the physics-oriented focus of the previous parts, there is a
gradual transition to biology and medicine with the increasing size
of the object studied. Finally, Part IV is dedicated to current
trends and novel techniques in radiation reserach and the
applications hence arising. It includes new developments in
radiotherapy and related cancer therapies, as well as technical
optimizations of accelerators and totally new equipment designs,
giving a glimpse of the near future of radiation-based medical
treatments."
The Routledge Handbook of Latin America and the Environment
provides an in-depth and accessible analysis and theorization of
environmental issues in the region. It will help readers make
connections between Latin American and other regions' perspectives,
experiences, and environmental concerns. Latin America has seen an
acceleration of environmental degradation due to the expansion of
resource extraction and urban areas. This Handbook addresses Latin
America not only as object of study, but also as a region with a
long and profound history of critical thinking on these themes.
Furthermore, the Handbook departs from the environment as a social
issue inextricably linked to politics, economy and culture. It will
be an invaluable resource for those wanting not only to understand
the issues, but also to engage with ideas about environmental
politics and social-ecological transformation. The handbook covers
a broad range organized in three areas: physical geography, ecology
and crucial environmental problems of the region, key theoretical
and methodological issues used to understand Latin America's
ecosocial contexts, and institutional and grassroots practices
related to more just and sustainable worlds. The Handbook will set
a research agenda for the near future and provide comprehensive
research on most subregions relative to environmental
transformations, challenges, struggles and political processes. It
stands as a fresh and much needed state of the art introduction for
researchers, scholars, post-graduates and academic audiences on
Latin American contributions to theorization, empirical research
and environmental practices.
Since the discovery of X-rays and radioactivity, ionizing
radiations have been widely applied in medicine both for diagnostic
and therapeutic purposes. The risks associated with radiation
exposure and handling led to the parallel development of the field
of radiation protection.
Pioneering experiments done by Sanche and co-workers in 2000 showed
that low-energy secondary electrons, which are abundantly generated
along radiation tracks, are primarily responsible for radiation
damage through successive interactions with the molecular
constituents of the medium. Apart from ionizing processes, which
are usually related to radiation damage, below the ionization level
low-energy electrons can induce molecular fragmentation via
dissociative processes such as internal excitation and electron
attachment. This prompted collaborative projects between different
research groups from European countries together with other
specialists from Canada, the USA and Australia.
This booksummarizes the advances achieved by these research groups
after more than ten years of studies on radiation damage in
biomolecular systems.
An extensive Part I deals with recent experimental and
theoretical findings on radiation induced damage at the molecular
level. It includes many contributions on electron and
positroncollisions with biologically relevant molecules. X-ray and
ion interactions are also covered. Part II addresses different
approaches to radiation damage modelling. In Part III biomedical
aspects of radiation effects are treated on different scales. After
the physics-oriented focus of the previous parts, there is a
gradual transition to biology and medicine with the increasing size
of the object studied. Finally, Part IV is dedicated to current
trends and novel techniques in radiation reserach and the
applications hence arising. It includes new developments in
radiotherapy and related cancer therapies, as well as technical
optimizations of accelerators and totally new equipment designs,
giving a glimpse of the near future of radiation-based medical
treatments."
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