Spanning from discoveries in fundamental immunology to industrial and commercial concerns, the study of vaccine adjuvants has developed into an exciting area of work with great, vital potential in innovating techniques in which adjuvants may steer the immune system towards the responses required by unmet vaccination needs. In Vaccine Adjuvants: Methods and Protocols, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products. Rather than describing individual adjuvants, the volume strives to include detailed, practical information on measuring the responses produced by adjuvants in order to be relevant to the widest array of experiments. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and versatile, Vaccine Adjuvants: Methods and Protocols will enable those already pursuing vaccine adjuvant research, while also serving to stimulate discussion on how to best standardize adjuvant testing in order to facilitate meaningful comparisons, and above all, to aid in the prediction of which new products will most effectively and safely help to solve the current challenges in vaccination.

Spanning from discoveries in fundamental immunology to industrial and commercial concerns, the study of vaccine adjuvants has developed into an exciting area of work with great, vital potential in innovating techniques in which adjuvants may steer the immune system towards the responses required by unmet vaccination needs. In Vaccine Adjuvants: Methods and Protocols, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products. Rather than describing individual adjuvants, the volume strives to include detailed, practical information on measuring the responses produced by adjuvants in order to be relevant to the widest array of experiments. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and versatile, Vaccine Adjuvants: Methods and Protocols will enable those already pursuing vaccine adjuvant research, while also serving to stimulate discussion on how to best standardize adjuvant testing in order to facilitate meaningful comparisons, and above all, to aid in the prediction of which new products will most effectively and safely help to solve the current challenges in vaccination.

The Late Roman fort at Yotvata is located in the southern Arava some 40 km north of Eilat/Aqaba (ancient Aila). The modern Hebrew name of the site is based on its suggested identification with biblical Jotbathah (Deut 10:7), where the Israelites encamped during their desert wanderings. The modern Arabic name of the site, Ein Ghadian, may preserve the ancient Roman name Ad Dianam. Because the Late Roman fort at Yotvata is visible as a low mound next to the Arava road, it has long been known to scholars. Each June between 2003 and 2007, Gwyn Davies (Florida International University) and Jodi Magness (University of North Carolina at Chapel Hill) co-directed excavations here. This volume provides the results of those excavations, adding substantially to our knowledge of Roman defenses in the third and fourth centuries of the Common Era, along the trade route that traversed the southern Arava and on the eastern frontier of the Empire.

This book contains thirteen papers on Roman archaeology from the tenth Theoretical Roman Archaeology Conference in London. The TRAC conference was held in April 2000, at the Institute of Archaeology and was divided into five different sessions. In the opening session, Representing Romans, the methodology of portraying the Romans to the wider world was explored. David Clarke and Fraser Hunter's paper outlines the challenge of designing appropiate gallery displays for the new National Museum of Scotland. In his paper, Francis Grew discusses the development of Roman London. Garrick Fincham's paper discusses the threat of overwhelming military intervention by the imperial power in colonial negotiations. Issues of ethnicity, gender, class and occupation within the later Roman army are addressed here. Miranda Green's paper presents an important discussion of the nature of human/stag hybrids in Iron Age and Gallo-Roman iconography, and Gillian Hawkes presents an analysis of food procurement and preparation encountered in Roman Britain. Gilly Carr considers the role of body decoration and grooming, arguing that individuals in different areas of south eastern Roman Britain made different cultural choices to structure their ethnic identities. The final set of papers focused on Constructing Childhood in the Roman World, reconsidering some long-standing truisms regarding the status and treatment of children in the Roman context. John Pearce examines Roman infant burial and the role religion plays in burial ceremony.