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Gene regulatory networks are the most complex, extensive control
systems found in nature. The interaction between biology and
evolution has been the subject of great interest in recent years.
The author, Eric Davidson, has been instrumental in elucidating
this relationship. He is a world renowned scientist and a major
contributor to the field of developmental biology.
The Regulatory Genome beautifully explains the control of animal
development in terms of structure/function relations of inherited
regulatory DNA sequence, and the emergent properties of the gene
regulatory networks composed of these sequences. New insights into
the mechanisms of body plan evolution are derived from
considerations of the consequences of change in developmental gene
regulatory networks. Examples of crucial evidence underscore each
major concept. The clear writing style explains regulatory
causality without requiring a sophisticated background in
descriptive developmental biology. This unique text supersedes
anything currently available in the market.
* The only book in the market that is solely devoted to the genomic
regulatory code for animal development
* Written at a conceptual level, including many novel synthetic
concepts that ultimately simplify understanding
* Presents a comprehensive treatment of molecular control elements
that determine the function of genes
* Provides a comparative treatment of development, based on
principles rather than description of developmental processes
* Considers the evolutionary processes in terms of the structural
properties of gene regulatory networks
* Includes 42 full-color descriptive figures and diagrams
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Works (Hardcover, Centenary ed)
Nathaniel Hawthorne, Edward H. Davidson, Claude M. Simpson, L. Neal Smith
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R3,934
Discovery Miles 39 340
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Ships in 10 - 15 working days
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The elections of 1998 bear out the thesis of this book: so far, the
Republicans in Congress are operating more like an old minority
party than the new majority party they've become. Still, Congress
has changed under Republican leadership and the Republicans have
changed, too. This volume of original essays by leading
congressional scholars explores the impact of the Republican
majority on Congress with attention to the history of the
institution and party characteristics present and future. For
students and scholars alike, the new majority of an old minority
provides a laboratory for political analysis that demonstrates
lasting effects. As Republicans learn to govern, the country will
no doubt learn something, too.
The elections of 1998 bear out the thesis of this book: so far, the
Republicans in Congress are operating more like an old minority
party than the new majority party they've become. Still, Congress
has changed under Republican leadership and the Republicans have
changed, too. This volume of original essays by leading
congressional scholars explores the impact of the Republican
majority on Congress with attention to the history of the
institution and party characteristics present and future. For
students and scholars alike, the new majority of an old minority
provides a laboratory for political analysis that demonstrates
lasting effects. As Republicans learn to govern, the country will
no doubt learn something, too.
The war on terrorism has raised profound questions of domestic
governance -not primarily about power or policy, but about the
capacities of government agencies, their personnel, procedures,
work habits and styles, and ability to interface with each other.
These are the "workways of governance." As the aftermath of the
tragic events of September 11, 2001, made very clear, shortcomings
and defects in the workways of governance are all too often
manifested only in times of crisis or scandal -after the damage is
done. How much better it would be to design for government a
version of the periodic physical examination, where tests of
various types, together with the physician's observations and the
patient's own testimony, combine to help define the patient's
status and prospects. The Workways of Governance project, sponsored
by the Governance Institute, was begun in 1997 in response to a
growing concern that institutions of national government have
evolved into structures and developed procedures and customs that
constrain their workers and hamper their collective effectiveness.
A unique feature of the project is the development of a periodic
review of the quality of institutional life and work in government.
Guidelines for evaluating and monitoring governmental entities will
be established, and implemented annually or biennially. The
resulting reports consist of both objectively measured data and
subjective evaluation, with the ultimate aim of generating positive
change toward improving the capacity of government. In this first
volume of analysis arising from the Workways of Governance project,
contributors apply these general guidelines to evaluate the leading
institutions of the federal government, as listed in the first
three articles of the Constitution: the House of Representatives,
the Senate, the presidency (focusing on White House organization
and staffing), the executive branch (focusing on the civil
service), and the federal judiciary.
Parliaments widely had been expected to decline in significance in
the later part of the 20th century, but instead they have developed
new and vital political roles and have innovated in their
institutional structure - most recurrently in newly organised or
invigorated parliamentary committees, not only in a few
parliaments, but as a global phenomenon.
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The American Elections of 2008 (Paperback)
Janet M. Box-Steffensmeier, Steven E. Schier; Contributions by Robert G Boatright, Janet M. Box-Steffensmeier, David Campbell, …
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R1,177
Discovery Miles 11 770
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Ships in 10 - 15 working days
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"The American Elections of 2008" assembles leading political
scientists and journalists to explain the election results and
their implications for America's future. Topics include financing
the elections, religion's influence, the media, and how the George
W. Bush legacy affected the outcome. The book also explores
Congressional behavior in the twenty-first century and discusses
how it affected election results in 2008.
"Genomic Control Process" explores the biological phenomena
around genomic regulatory systems that control and shape animal
development processes, and which determine the nature of
evolutionary processes that affect body plan. Unifying and
simplifying the descriptions of development and evolution by
focusing on the causality in these processes, it provides a
comprehensive method of considering genomic control across diverse
biological processes.
This book is essential for graduate researchers in genomics,
systems biology and molecular biology seeking to understand deep
biological processes which regulate the structure of animals during
development. Covers a vast area of current biological research to
produce a genome oriented regulatory bioscience of animal life
Places gene regulation, embryonic and postembryonic development,
and evolution of the body plan in a unified conceptual
frameworkProvides the conceptual keys to interpret a broad
developmental and evolutionary landscape with precise experimental
illustrations drawn from contemporary literatureIncludes a range of
material, from developmental phenomenology to quantitative and
logic models, from phylogenetics to the molecular biology of gene
regulation, from animal models of all kinds to evidence of every
relevant typeDemonstrates the causal power of system-level
understanding of genomic control process
Conceptually organizes a constellation of complex and diverse
biological phenomenaInvestigates fundamental developmental control
system logic in diverse circumstances and expresses these in
conceptual modelsExplores mechanistic evolutionary processes,
illuminating the evolutionary consequences of developmental control
systems as they are encoded in the genome"
'Reimagining Business Education' discusses the rationale for, and
design of, the first Business Education Jam. It reviews key
challenges facing business education and articulates a vision for
how the role and delivery of business education could be
reimagined. This book is critically important during a time when
business schools, as an industry, struggle to identify the
innovations necessary to meet the needs of a changing world. The
Jam was the first open platform for dialogue of its kind for
business education and continues to make an impact - including use
by Schools and Deans around the world to guide strategic planning
efforts; program directors as they drive innovation in their
programs; and industry executives as they identify ways to better
engage with business education. This book takes this collaborative
effort a step further to break down traditional models and
structures as we seek to reimagine the future of business education
in a more open and connected world.
Parliaments widely had been expected to decline in significance in
the later part of the 20th century, but instead they have developed
new and vital political roles and have innovated in their
institutional structure - most recurrently in newly organised or
invigorated parliamentary committees, not only in a few
parliaments, but as a global phenomenon.
'Grandma's acting worried, and looking very grim. She never knows
each morning, just what the cat's dragged in!' In this hilarious,
lighthearted new picture book by the 2017 Notable Book
award-winning author Joy H. Davidson, a week at Grandma's house
descends into chaos as the cat brings a range of increasingly icky
creatures inside every night that have to play dead to avoid being
eaten by the hungry feline. Children will love chanting along with
the refrain 'OH NO NO NO! Look what the cat dragged in' and will
delight in Jenny Cooper's gleefully gory illustrations. And, of
course, every reader will be eager to find out how Grandma finally
manages to stop that incorrigible cat from getting up to mischief!
This book provides an overview of the field of flow and heat
transfer in porous medium and focuses on presentation of a
generalized approach to predict drag and convective heat transfer
within porous medium of arbitrary microscopic geometry, including
reticulated foams and packed beds. Practical numerical methods to
solve natural convection problems in porous media will be presented
with illustrative applications for filtrations, thermal storage and
solar receivers.
"This book should be required reading for professionals in early
education and makes thought-provoking reading for anyone aware of
his or her own cultural blinkers."-Penelope Leach, New York Times
Book Review "[An] important study of the way preschools both
reflect and affect social change. . . . A must read for those who
take social issues seriously."-Carole C. Kemmerer, Los Angeles
Times As the numbers of mothers in the workforce grows, the role of
the extended family diminishes, and parents feel under greater
pressure to give their children an educational headstart,
industrialized societies are increasingly turning to preschools to
nurture, educate, and socialize young children. Drawing on their
backgrounds in anthropology, human development, and education,
Tobin, Wu, and Davidson present a unique comparison of the
practices and philosophies of Japanese, Chinese, and American
preschool education and discuss how changes in childcare both
reflect and affect larger social change. The method used is
innovative: the authors first videotaped a preschool in each
culture, then showed the tapes to preschool staff, parents, and
child development experts. Through their vivid descriptions of a
day in each country's preschools, photographs made from their
videotapes, and Chinese, Japanese, and American evaluations of
their own and each other's schools, we are drawn into a
multicultural discussion of such issues as freedom, conformity,
creativity, and discipline.
Surveys the pre-Christian beliefs of the Scandinavian and Germanic
people. This title provides an introduction to this subject, giving
basic outlines to the sagas and stories, and helps identify the
character traits of the well known as well as the lesser gods of
the age.
This book is a study of the slow growth of the movement for reform,
the basis of opposition, the gradual success that was achieved, and
the close relationship between the regulation of child labor and
the development of public education in the South--the two movements
necessarily accompanying and supplementing each other. Originally
published in 1939. A UNC Press Enduring Edition - UNC Press
Enduring Editions use the latest in digital technology to make
available again books from our distinguished backlist that were
previously out of print. These editions are published unaltered
from the original, and are presented in affordable paperback
formats, bringing readers both historical and cultural value.
The three-volume handbook showcases the state of the art in the use
of concentrated sunlight to produce electricity, industrial process
heat, renewable fuels, including hydrogen and low-carbon synthesis
gas, and valuable chemical commodities. The handbook illustrates
the value and diversity of applications for concentrating solar
power to contribute to the expanding decarbonization of multiple
cross-cutting energy sectors.Volume 1: Concentrating Solar Thermal
Power, provides an overview of key technologies, principles, and
challenges of concentrating solar power (CSP) as well as the use of
concentrating solar thermal for process heating and district
markets. The ten chapters of this volume provide the reader with
the technical background on the solar resource for concentrating
solar thermal, the principles and design of concentrating optics,
and descriptions of state-of-the-art and emerging solar collector
and receiver technologies, thermal storage and thermal-to-electric
conversion and power cycles for CSP. It also contains a
comprehensive summary of operations and maintenance requirements
for CSP plants, and commercial CSP plants and markets around the
world.Volume 2, Solar Thermochemical Processes and Products, covers
the use of concentrated solar radiation as the heat source to drive
endothermic chemical reactions to produce renewable fuels and
valuable chemical commodities, equivalently storing solar energy in
chemical bonds. The thermodynamic underpinnings of a number of
approaches to produce fuel and results of demonstrations of solar
thermochemical reactors for these processes at prototype scale are
presented. Processes presented include thermochemical metal oxide
reduction/oxidation cycles to split water and carbon dioxide solar
chemical looping reformation of methane to produce synthesis gas,
high temperature electrochemistry, and gasification of biomass.
Research on the thermochemical storage for CSP and high temperature
production of cement and ammonia to illustrate the use concentrated
solar energy to produce valuable chemical products are also
included.Volume 3 contains reprinted archival papers to support and
supplement the material in Volumes 1 and 2. These papers provide
background information on the economics and alternative use cases
of CSP not covered in Volume 1, and expand on the material related
to the chapter topics presented in Volume 2. Potential
commercialization, such as prototype and demonstration projects,
are highlighted. The papers are intended as a starting point for a
more in-depth study of the topics.
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