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Spontaneous intracerebral haemorrhages are the most dangerous
complication of cerebral vascular disease. Because of their
frequency and the fact that they lead to serious injuries,
prolonged disabilities and, often, death, they have acquired an
enormous significance, both medically and socially. Their precise
diagnosis, location, wide extent and accomp ying manifestations
were for a very long time uncertain and, in small and deeply
situated haematomas, these factors were impossible to determine.
Diagnosis was confirmed by the clinical picture, by angiography and
sometimes by ventriculography and included, in the main, both lobar
and more extensive haematomas. The results of operative treatment
following the first attempt of H. Cushing in 1903 were poor and
remained unsatisfactory in spite of the endeavours of numerous
authors (Guillaume et al. 1956; Lazorthes 1956; McKissock et al.
1959; Luessenhop 1967 and many others). Especially for the most
frequent and typically hypertensive haematomas in the region of the
internal, capsule, the opinion was often expressed that operative
treatment was useless.
Microsurgery has brought about important changes and progress in
the treatment of cere bral aneurysms in recent years. Only 12 years
ago McKissock, one of the most experienced surgeons in the
treatment of aneurysms pompared the results of operative and
nonoperative treatment. He found that mortality and morbidity of
cerebral aneurysms was not significantly affected by whether the
patients have been operated upon or not. This view is held by many
neursurgeons, and was confirmed by results of the Co-operative
Study in 1969. In the review on treatment of aneurysms in Progress
in Neurological Surgery in 1969, techniques such as encasement with
plastic compounds, piloinjection, stereotactic copper or electric
thrombosis and metallic thrombosis and profound hypothermia in
anaesthesia were listed. In general, these techniques now seem to
be of little more than historical interest. Progress in recent
yeats has been so enormous that one may perhaps gain the impreSSion
that the main problems in the treatment of aneurysms have been
solved and that there are no more to be surmounted. This is
dangerous and complacent thinking, such as Lord Moynihan indulged
in during the thirties. For this reason we thought that the time
had come to assemble a group of experts who could discuss the
various unsolved and contro versial problems of aneurysm surgery in
the friendly and relaxed atmosphere of a "work shop.""
The rapid development of diagnostic and therapeutic procedures in
the management of spinal angiomas has opened up new possibilities
and provided better chances for the patients concerned. The
greatest impetus to this pro gress was given by the introduction of
selective and superselective spinal angiography, microsurgical
technique, and embolization. These sophisticated techniques and the
skill required for their use are far from being routine in the
neurosurgical and neuroradiologic departments. In spite of the
rarity of spinal angiomas, the application of the above-mentioned
procedures is the prerequisite for improving early diagnosis and
giving timely adequate treat ment. Delay in diagnosis and treatment
are still the main cause of unsatisfac tory results. In the last 10
-20 years, several groups in Europe and the USA have done important
and fundamental work in introducing and developing the diganos tic
and therapeutic armamentarium. Based on the pioneering work of
their teachers and the classic contribution of Wyburn - Mason in
1943, they simultaneously improved the morphologic, physiologic,
and clinical basis of our knowledge. Although progress is going on
and many problems have to be solved, the general principles of
clinical diagnosis, operative treatment, and embolization have been
laid down and are to be published in a special monograph on this
topic."
The basic principles of the management of cerebral arteriovenous
mal- formations were established during the first phase of the
neurological attack on these problems between 1930 and 1960. The
leaders were CUSHING, BAILEY and DANDY, but principally OUVECRONA,
and in Ger- many TONNIS. The experience gained showed that complete
excision of the arteriovenous angioma was the only certain cure,
and therefore was the procedure of choice. In the present second
phase important advances should be made and indeed are occurring.
New diagnostic techniques such as total angio- graphy, selective
and superselective angiography, intraoperative and fluorescein
angiography, and the EMI-scanner have been developed. The
pathophysiological aspects have been further investigated by
indirect and direct measurement of local and general cerebral blood
flow. Parallel with these developments operative technique itself
has been improved and modified by new methods. A more aggressive
attitude has been stimulated towards those angiomas, which had to
be regarded as inoperable only a few years ago. Among these many
im- provements and technical advances include microsurgical
techniques, combined stereotactic and microsurgical procedures,
artificial emboliza- tion of different kinds and the cryosurgical
management. Multiple variables such as the age of the patient, the
type, localization, and size of the angioma, its clinical picture
and the possible complica- tions, such as hemorrhage have been
analysed and are understood better. These factors influence the
indication for, and choice of, the appropriate procedure to a great
extent.
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