|
Showing 1 - 1 of
1 matches in All Departments
This volume contains the proceedings of an International Symposium
on `Second Messenger Systems - Molecular, Cellular and Behavioural
Aspects', which was held at Tobago on June 16-17, 1994. The
interaction of an extracellular agonist (First Messenger) with its
plasma membrane receptor leads to the transmission of a signal
across the cell membrane and results in the production and/or
activation of other signalling molecules (Second Messengers). These
Second Messengers control the action of many protein kinases and
protein phosphatases and so lead to cellular responses. Although
the biochemical basis of the transduction of signals in the main
signalling systems in eukaryotic cells is probably largely known,
intensified research is ongoing in the following areas: the
discovery of specific substrates for many protein kinases,
elucidation of the biological significance of the differential
tissue expression and heterogeneity of many signalling proteins,
and the unravelling of diverse interactions (such as signal
potentiation, synergism, antagonism and neuronal co-transmission)
between signalling systems. As knowledge from such studies
accumulates, it is becoming clear that the `cross talk'
interactions between signalling systems are important features of
dynamic cell regulation. This volume is designed to summarize some
aspects of the current work on various Second Messenger Systems and
the integration of signals with respect to plasma membrane
receptors. Second Messenger generation and degradation, protein
kinase and phosphatase, cell cycle control, and cellular learning
and memory.
|
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.