This book gathers original research papers presented at the 4th International Conference on Computational Mathematics and Engineering Sciences, held at Akdeniz University, Antalya, Turkey, on 20-22 April 2019. Focusing on computational methods in science, mathematical tools applied to engineering, mathematical modeling and new aspects of analysis, the book discusses the applications of mathematical modelling in areas such as health science, engineering, computer science, social science, and economics. It also describes a wide variety of analytical, computational, and numerical methods. The conference aimed to foster cooperation between students and researchers in the areas of computational mathematics and engineering sciences, and provide a platform for them to share significant research ideas. This book is a valuable resource for graduate students, researchers and educators interested in the mathematical tools and techniques required for solving various problems arising in science and engineering, and understanding new methods and uses of mathematical analysis.