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This new volume looks at the applications of biomarkers as
important tools for herbal drug discovery, presenting research on
phytoconstituents with advanced nanotechnological applications for
healthcare benefits. Herbal drug discovery based on biomarkers is
an emerging area in complementary and alternative medicine that has
tremendous potential in healthcare. Conventional medications have
limited efficacy and high toxicity, whereas herbal drugs are said
to provide wide structural diversity that is not usually seen with
conventional/synthetic drug molecules. Recognition of various
herbal constituents, such as terpenoids, fatty acids, flavonoids
and steroids, are well explored in the management and treatment of
various disorders in this volume. These agents target various
biomarkers such as nitric oxide (NO), cytokines, chemokines,
adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic
acid. Biomarkers as Targeted Herbal Drug Discovery: A
Pharmacological Approach to Nanomedicines discusses
phytoconstituent-based nanotherapeutics with applications for some
specific health issues, such as arthritis, leishmanicidal,
cardiovascular diseases, cancer, ocular disorders, etc.
This new volume looks at the applications of biomarkers as
important tools for herbal drug discovery, presenting research on
phytoconstituents with advanced nanotechnological applications for
healthcare benefits. Herbal drug discovery based on biomarkers is
an emerging area in complementary and alternative medicine that has
tremendous potential in healthcare. Conventional medications have
limited efficacy and high toxicity, whereas herbal drugs are said
to provide wide structural diversity that is not usually seen with
conventional/synthetic drug molecules. Recognition of various
herbal constituents, such as terpenoids, fatty acids, flavonoids
and steroids, are well explored in the management and treatment of
various disorders in this volume. These agents target various
biomarkers such as nitric oxide (NO), cytokines, chemokines,
adhesion molecules, NF- k , lipoxygenase (LOX), and arachidonic
acid. Biomarkers as Targeted Herbal Drug Discovery: A
Pharmacological Approach to Nanomedicines discusses
phytoconstituent-based nanotherapeutics with applications for some
specific health issues, such as arthritis, leishmanicidal,
cardiovascular diseases, cancer, ocular disorders, etc.
Nanotherapeutics in Cancer Vaccination and Challenges consolidates
the current research on cancer nanomedicine and therapeutic cancer
vaccination to explore the most effective and promising avenues.
The book covers cancer vaccines before exploring nanotherapeutics,
DNA and mRNA vaccines in cancer treatment. Finally, it considers
regulatory and industrial perspectives on cancer vaccination and
nanotherapeutics. This resource will be useful for pharmaceutical
scientists and researchers focused on biomedical engineering,
chemical engineering, vaccine development, and cancer
immunotherapy, along with advanced students in these subjects.
Cancer is arguably the most complex and challenging disease known
to mankind. Over the last two-decades, significant advancements
have been made in new and novel concepts of cancer nanomedicines.
Therapeutic cancer vaccines may be utilized to inhibit further
growth of advanced cancers and/or relapsed tumors that are
refractory to conventional therapies, such as surgery, radiation
therapy and chemotherapy.
This volume provides an interdisciplinary perspective of applying
Next Generation Sequencing (NGS) technology to cancer research. It
aims to systematically introduce the concept of NGS, a variety of
NGS platforms and their practical implications in cancer
biology.This unique and comprehensive text will integrate the
unprecedented NGS technology into various cancer research projects
as opposed to most books which offer a detailed description of the
technology. This volume will present true experimental results with
concrete data processing pipelines, discuss the bottleneck of each
platform for real project in cancer research. In additional, single
cancer cell sequencing as the proof of concept will be introduced
in this book, along with cutting-edge information provided will
help the intended audience to develop a comprehensive understanding
of the NGS technology and practical whole genome sequencing data
analysis and rapidly translate into their own research,
specifically in the field of cancer biology.
Latest generation sequencing revolutionizes the fields of cancer
research and oncology. This follow-up volume focuses more
extensively on single cell sequencing of cancer and trials in drug
resistance. Another exciting feature is the bioinformatics tools
given, that can be used on cancer genome studies. Scientists around
the world are attempting to find the root cause of cancer. A
reasonable cancer treatment plan and potential cure is more
optimistic now with the unfolding of the cancer genome. The
collective knowledge of how to leverage next generation sequencing
in cancer research is paving the way. The important information
provided in this volume will move the field forward in developing
novel targeted cancer therapies.
This volume provides an interdisciplinary perspective of applying
Next Generation Sequencing (NGS) technology to cancer research. It
aims to systematically introduce the concept of NGS, a variety of
NGS platforms and their practical implications in cancer
biology.This unique and comprehensive text will integrate the
unprecedented NGS technology into various cancer research projects
as opposed to most books which offer a detailed description of the
technology. This volume will present true experimental results with
concrete data processing pipelines, discuss the bottleneck of each
platform for real project in cancer research. In additional, single
cancer cell sequencing as the proof of concept will be introduced
in this book, along with cutting-edge information provided will
help the intended audience to develop a comprehensive understanding
of the NGS technology and practical whole genome sequencing data
analysis and rapidly translate into their own research,
specifically in the field of cancer biology.
Nanoformulation Strategies for Cancer Treatment provides an
up-to-date review on current developments and regulatory and
clinical challenges in the field of nanopharmaceuticals and the
effective treatment of diverse varieties of cancer. This important
reference source is ideal for biomaterials scientists and
pharmaceutical scientists working in the area of cancer diagnosis
and therapy. Due to the high cost of traditional cancer treatment
types, researchers have increasingly looked for new ways to augment
the therapeutic performance of existing drug candidates. The use of
nanotechnology-based approaches have gained significant momentum,
thus leading to the launch of a series of new drug products. As
nanopharmaceuticals improve the therapeutic performance of cancer
therapy drugs, but also provide opportunities for site-specific
drug targeting in tumors, this work is a welcomed resource on the
topics discussed.
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