No other neurological condition allows the same opportunities for an intracranial electrophysiological study of the human brain as epilepsy does. Epileptic surgery is designed to remove the epileptic focus from the human brain, thereby effecting either cure or substantial reduction of seizures in an individual with an otherwise intractable condition. Its use as a treatment modality dates from the late 19th century, and it has become a widely used treatment option throughout the world in the last 20-30 years. The complexity of epilepsy cases in surgical centres, and the need for invasive electrode studies for pre-surgical evaluation, are both greatly increasing. Invasive Studies of the Human Epileptic Brain is the definitive reference text on the use of invasive electroencephalographic (EEG) diagnostic studies in human epilepsy. Written by some of the most renowned epilepsy experts of the 20th and 21st centuries, the authors provide their expertise and insights into the identification and mapping of intracranial epileptiform and non-epileptiform activity, mapping of the human brain function, and approaches in the use of invasive electroencephalography in a variety of clinical situations. The book is organized into an easily readable series of chapters and is brilliantly illustrated with case studies; each providing an intuitively comprehensive approach to invasive brain studies.

Deep brain stimulation has been used effectively for many years in patients suffering from Parkinson's disease. Now, we are seeing neurologists and neurosurgeons using electric pulse generators (that can be compared in one sense to the cardiac pacemaker) to block abnormal activity, i.e. epileptic fits. With promising research results that show how electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures, Hans Lüders and his team of contributors have summarized all the available literature into one volume. Deep Brain Stimulation and Epilepsy should provide the epileptologist and neurosurgeon with a solid background about deep brain stimulation and its application to epilepsy.

Textbook of Epilepsy Surgery" "covers all of the latest advances in the surgical management of epilepsy. The book provides a thorough understanding of epileptogenic mechanisms in etiologically different types of epilepsy and explains neuronavigation systems. It discusses new neuroimaging techniques, new surgical strategies, and more aggressive surgical approaches in cases with catastrophic epilepsies. The contributors also analyze the improved statistics of surgical outcome in different epilepsy types.

The book follows a systematic approach to the diagnostic evaluation of patients who are candidates for epilepsy surgery. It first discusses the general principles of surgery, and then describes the presurgical evaluation according to the six zones (symptomatogenic, irritative, ictal onset, epileptic lesion, functional deficit, and epileptogenic zone). This series of chapters concludes with the description of the Epilepsy Surgery Management Meeting, an essential and indispensable part of the surgical evaluation.

The book next incorporates detailed discussions of the cortical mapping techniques and the numerous surgical techniques. This is followed by the post-surgical medical management and a discussion of the surgical outcome. Finally, selected case studies are presented, along with protocols for the storage and processing of brain tissue for molecular studies. This definitive textbook is an invaluable reference for neurologists, neurosurgeons, epilepsy specialists, and those interested in epilepsy and its surgical treatment.