Nanostructured materials with tailored properties are regarded as a fundamental element in the development of future science and technology. Research is still ongoing into the nanosized construction elements required to create functional solids. The recently developed technique, nanocasting, has great advantage over others in terms of the synthesis of special nanostructured materials by the careful choice of suitable elements and nanoengineering steps. This new book summarizes the recent developments in nanocasting, including the principles of nanocasting, syntheses of novel nanostructured materials, characterization methods, detailed synthetic recipes and further possible development in this area. The book focuses on the synthesis of porous solids from the viewpoint of methodology and introduces the science of nanocasting from fundamental principles to their use in synthesis of various materials. It starts by outlining the principles of nanocasting, requirements to the templates and precursors and the tools needed to probe matter at the nanoscale level. It describes how to synthesize nano structured porous solids with defined characteristics and finally discusses the functionalization and application of porous solids. Special attention is given to new developments in this field and future perspectives. A useful appendix covering the detailed synthetic recipes of various templates including porous silica, porous carbon and colloidal spheres is included which will be invaluable to researchers wanting to follow and reproduce nanocast materials. Topics covered in the book include: * inorganic chemistry * organic chemistry * solution chemistry * sol-gel and interface science * acid-base equilibria * electrochemistry * biochemistry * confined synthesis The book gives readers not only an overview of nanocasting technology, but also sufficient information and knowledge for those wanting to prepare various nanostructured materials without needing to search the available literature.

The recent explosion in the use of analytical chemistry, particularly in the biological sciences, has led to a need for fast, reliable and highly sensitive tools able to handle small sample sizes. This book illustrates how microfluidics and lab-on-a-chip devices can satisfy the growing need for miniaturized and enhanced analysis. They lend themselves well to mass spectrometric detection as they use samples in the low microlitre range and are handled on a chip. Miniaturization and Mass Spectrometry focuses on one particular technique, mass spectrometry, whose popularity has increased dramatically in the last two decades with the increase in use of biological analysis and the development of two "soft" ionization techniques, ESI and MALDI. These enable the analysis of large but fragile biological molecules such as DNA, proteins and oligosaccharides. The book starts with an introduction to the coupling of microfluidics to mass spectrometry techniques. It then goes on demonstrate the advantages of such a coupling: the MS analysis benefits from improved sample preparation when performed on a chip while MS yields more information on the sample handled on the chip compared to conventional optical detection. A history on the developments in this field, starting from the off-chip coupling to the on-chip ionization, is also provided. Daniel Figeys, a pioneer in the development of microfluidic systems for MS analysis, describes the early beginnings of this hyphenated analysis technique. Solutions to couple microfluidic systems to the two most popular ionization methods, ESI and MALDI, are presented throughout the chapters. Various examples are given of the application of this microfluidics-MS hyphenated analysis technique to proteomics, metabolomics, organic chemistry and forensics. Coverage is not limited to academic research. The development of commercialized systems and their current use for routine biological analysis are also presented. Lastly, a future vision of the integration of the mass spectrometer on the chip is raised, as a last step to yield fully portable systems for on-site analysis.

Major technology shifts do not happen overnight and rarely are they the result of a single breakthrough discovery. Nowhere is this more true than for the broad set of enabling technologies that we have come to simply call "nanotechnology." Rather than standing on the shoulders of a few intellectual giants, nanotechnologies are created by tens of thousands of researchers and scientists working on minute and sometimes arcane aspects of their fields of expertise in areas as diverse as medicine, telecommunications, solar cells, filtration, coatings, or ever smaller transistors for electronic devices. They come from different sciences, live in different parts of the world and work for different organizations (government laboratories, industry laboratories, universities, private research facilities) and follow their own set of rules - get papers reviewed and published; achieve scientific recognition from their peers; struggle to get funding for new ideas; look to make that breakthrough discovery that leads to the ultimate resumU item - a nobel prize; get pushed by their funders to secure patent rights and commercialize new discoveries. This book puts a spotlight on some of the scientists who are pushing the boundaries of technology and it gives examples of their work and how they are advancing knowledge one little step at a time. The book shatters the monolithic term "nanotechnology" into the myriad of facets that it really is. It is a journey through the world of nanotechnology research and development, taking a personal look at how nanotechnologies get created today and by whom. The book covers 122 specific research projects that are happening in laboratories around the world and provides commentaries from the scientists in their own words. However, the collection of stories in this book barely scratches the surface of the vast and growing body of research that leads us into the nanotechnology age. The selection presented in the book is not meant to rank some laboratories and scientists higher than others, nor to imply that the work introduced in the book is more important or valuable than all the work that is not covered. The intention is to give the interested reader an idea of the incredibly diverse aspects that make up nanotechnology research and development - the results of which will bring about a new era of industrial and medical technologies. Nanoscience and nanotechnology research is a truly multidisciplinary and international effort. Each of the chapters is based on a particular scientific paper that has been published in a peer-reviewed journal and, while each story revolves around one or two scientists who were interviewed for this book, many, if not most, of the scientific accomplishments covered in the book are the result of collaborative efforts by several scientists and research groups, often from different organizations and from different countries. The book is different to other books in this field because it provides a novel human touch to nanotechnology research by not only covering a wide range of research topics but also the (often nameless) scientists behind this research. The book is a collection of Spotlight articles from the popular Nanowerk website and each article has been crafted with the author(s) of a scientific paper and signed off by them prior to being posted on Nanowerk. The book is intended for two broad groups of audiences - scientists and nanoscience students who want a bite-size, quick read to get a good first impression of what nanotechnologies are about and how they affect not only their own field but also neighbouring fields and other scientific disciplines further away. And a non-scientific readership that needs to (because it affects their organization and they have to acquaint themselves with nanotechnology) or wants to get a 'non-threatening' (i.e. no formulas, complex diagrams, or unexplained scientific terms) introduction, written by a non-scientist for non-scientists."

The progress of today's science and technology encounters an increasing demand for finer and more efficiently performing materials with properties superior over those of current and hence ageing devices. Whether this is concerned with electronics or drug delivery, cancer diagnostics or alternative energy sources, the search for means of miniaturizing the existing materials or devising fundamentally new components with higher capacities appears to be relentless. A saving solution to this is widely proposed as the design and fabrication of nanostructures, molecular architectures with dimensions featured below 100 nm. Replicating Nature's designs faithfully reproduced over millions of years provides perhaps the most straightforward route to success. Nature offers examples of nanodefined self-assemblies in virtually all levels of biological organization. However explicit guidance to the fabrication of functional or specialist nanostructures is of paramount importance.

Nanotechnology is often referred to as building nanoscale structures from bottom up. However, while it is visually clear what is at "up" little is given and understood what is at the "bottom." This new book gives the notion of and provides rules for building nanostructures from basics - the very bottom. The main objective of this publication is to bring together contemporary approaches for designing nanostructures that employ naturally derived self-assembling motifs as synthetic platforms.

The book has been written to satisfy the demands that motivate the search for and principles that prove to help the design of novel nanostructures. The overall goal is to compile the existing understanding of rules that govern biomolecular self-assembly into a practical guide to molecular nanotechnology. It is written in the shape of a review referenced as fully as permissible within the context of biomolecular design, which forms a general trend throughout.

The volume is composed of three core chapters focusing on three prominent topics of applied nanotechnology where the role of nanodesign is predominant. The three key areas from which popular highlights can be drawn are:

-employing the genetic repository, DNA, for creating various geometric nanoscale objects and patterns
-the empirical pursuit of an artificial virus, a magic bullet in gene therapy
-designing artificial extracellular matrices for regenerative medicine

Specific applications that arise from designed nanoscale assemblies as well as fabrication and characterization techniques are of secondary importance and whenever they appear serve as progress and innovation highlights.

The book takes an unconventional approach in delivering material of this kind. It does not lead straight to applications or methods as most nanotechnology works tend to do, but instead it focuses on the initial and primary aspect of "nano" rather than on "technology." Nanodesign is unique in its own field - illustrations are essential and the cohort of brilliant bioinspired designs reported to date form a major part of the publication. In addition, key bibliographic references are covered as fully as possible. A special appendix giving a short list of leading world laboratories engaged in bioinspired nanodesign is also included.

This exciting new book is a unique compilation of data from a wide range of chemical and spectroscopic instrumentation and the integration of nanostructure characterisation drawn from physical, chemical, electrochemical, spectroscopic and electron microscopic measurements. It fills a gap in the current nanomaterials literature by documenting the latest research from scientific journals and patent literature to provide a concise yet balanced and integrated treatment of an interesting topic: titanium oxide nanostructures within the emerging fashionable area of nanomaterials. Of particular interest are the following key chapters: * Modification and Coating Techniques - provides a unique summary and discussion of available techniques to coat surfaces with nanostructured materials * Chemical Properties - relates structure to surface chemistry and hence applications * Structural and Physical Properties - reviews the relationship between nanostructure and physical properties providing a basis for the rationalisation of applications The book, a valuable reference point, is aimed at professionals, postgraduates and industrial research workers in nanomaterials. Readers will gain a knowledge of the methods for synthesising nanomaterials as well as an understanding of their structure and resulting physical characteristics and a knowledge of their (existing and potential) applications.