This collection features four peer-reviewed reviews of septoria tritici blotch in cereals. The first chapter reviews the various methods for managing septoria tritici blotch (STB), from the the use of fungicides to marker-assisted breeding for increased resistance to STB. It also surveys research on the molecular basis of host-pathogen interactions in STB. The second chapter reviews current research on the main fungal diseases affecting barley, focussing on biotrophic foliar diseases, such as stem rust and powdery mildew, as well as necrotrophic diseases, such as septoria tritici blotch and fusarium head blight. The chapter also discusses the implications for achieving sustainable resistance to the pathogens responsible for these diseases. The third chapter addresses advances in understanding the epidemiology of septoria tritici blotch in the major cereal crops. The chapter also reviews the taxonomy and life cycle of Zymoseptoria tritici - the cause of septoria tritici blotch, as well as the economic impact of the pathogen. The final chapter reviews recent research on genetic resistance loci and breeding strategies based on both conventional and biotechnology-based breeding approaches to achieve durable resistance to septoria tritici blotch infection, whilst simultaneously minimising the risk of grain yield losses.