High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.
HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.
* Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory
* Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)
* Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

Originally written in Danish in 1980, Pink Moon was the first biography of Nick Drake, and remains the only one to include exclusive interviews with the singer's parents, Rodney and Molly Drake. In this new, significantly updated edition, available in English for the first time, author and poet Gorm Henrik Rasmussen reveals more from his visits to the Drakes in their home Far Leys - the first, just five years after the death of their troubled son. Rasmussen includes new interviews with Nick's friends and collaborators plus extracts taken from his eight-year correspondence with the Drakes, and from telephone conversations he had with Rodney every month over four years. Full of intimate detail about the last three years of Nick's life spent at his childhood home, Pink Moon - A Story about Nick Drake is a personal, original, and moving retelling of the life, death, and posthumous rise of a poet and guitarist who was strangely unsuited for his own time, and is more popular now than he ever was in life. -- .

Originally written in Danish in 1980, Pink Moon was the first biography of Nick Drake, and remains the only one to include exclusive interviews with the singer's parents, Rodney and Molly Drake. In this new, significantly updated edition, available in English for the first time, author and poet Gorm Henrik Rasmussen reveals more from his visits to the Drakes in their home Far Leys - the first, just five years after the death of their troubled son. Rasmussen includes new interviews with Nick's friends and collaborators plus extracts taken from his eight-year correspondence with the Drakes, and from telephone conversations he had with Rodney every month over four years. Full of intimate detail about the last three years of Nick's life spent at his childhood home, Pink Moon - A Story about Nick Drake is a personal, original, and moving retelling of the life, death, and posthumous rise of a poet and guitarist who was strangely unsuited for his own time, and is more popular now than he ever was in life. -- .