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NMR Chemical Exchange in Mapping the Protein-Ligand Binding Site (Paperback): Janarthanan Krishnamoorthy, Henry Yu Keung Mok NMR Chemical Exchange in Mapping the Protein-Ligand Binding Site (Paperback)
Janarthanan Krishnamoorthy, Henry Yu Keung Mok
R1,318 Discovery Miles 13 180 Ships in 10 - 15 working days

Chemical exchange is one of the most extensively studied phenomenon in NMR spectroscopy to identify and establish the mechanism of interaction between molecules of interest (protein-ligand). While the exchange regimes are classified into three types based on the experimentally observed spectral pattern, the theory underlying all these three regimes is general. In order to delineate the mechanism of interaction through chemical exchange, mechanism dependent ligand correction and evaluation of population are necessary. For a simple system the data analysis is easier compared to the complex systems, where both the ligand correction and parameter optimization are to be performed simultaneously. This analytical difficulty has been overcome by adopting a genetic algorithm based approach for data analysis using numerical method. The computational implementation is available in the form of open source C programs: 'Auto-FACE' for fast chemical exchange and 'AUTOMEX' for all exchange regimes.

Within and Without the Nation - Canadian History as Transnational History (Paperback): Karen Dubinsky, Adele Perry, Henry Yu Within and Without the Nation - Canadian History as Transnational History (Paperback)
Karen Dubinsky, Adele Perry, Henry Yu
R1,517 Discovery Miles 15 170 Ships in 10 - 15 working days

In some ways, Canadian history has always been international, comparative, and wide-ranging. However, in recent years the importance of the ties between Canadian and transnational history have become increasingly clear. Within and Without the Nation brings scholars from a range of disciplines together to examine Canada's past in new ways through the lens of transnational scholarship. Moving beyond well-known comparisons with Britain and the United States, the fifteen essays in this collection connect Canada with Latin America, the Caribbean, and the wider Pacific world, as well as with other parts of the British Empire. Examining themes such as the dispossession of indigenous peoples, the influence of nationalism and national identity, and the impact of global migration, Within and Without the Nation is a text which will help readers rethink what constitutes Canadian history.

Thinking Orientals - Migration, Contact, and Exoticism in Modern America (Paperback, Revised): Henry Yu Thinking Orientals - Migration, Contact, and Exoticism in Modern America (Paperback, Revised)
Henry Yu
R1,458 Discovery Miles 14 580 Ships in 10 - 15 working days

Thinking Orientals is a groundbreaking study of Asian Americans and the racial formation of twentieth-century American society. It reveals the influential role Asian Americans played in constructing the understandings of Asian American identity. It examines the unique role played by sociologists, particularly sociologists at the University of Chicago, in the study of the "Oriental Problem" before World War II. The book also analyses the internment of Japanese Americans during the war and the subsequent "model minority" profile.

Thinking Orientals - Migration, Contact, and Exoticism in Modern America (Hardcover): Henry Yu Thinking Orientals - Migration, Contact, and Exoticism in Modern America (Hardcover)
Henry Yu
R3,925 Discovery Miles 39 250 Ships in 10 - 15 working days

Thinking Orientals is a groundbreaking study of Asian Americans and the racial formation of twentieth-century American society. It reveals the influential role Asian Americans played in constructing the understandings of Asian American identity. It examines the unique role played by sociologists, particularly sociologists at the University of Chicago, in the study of the "Oriental Problem" before World War II and also analyzes the internment of Japanese Americans during the war and the subsequent "model minority" profile.

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