This work book contributes to the knowledge about human settlements in the Isla Grande of Tierra Del Fuego by the hunter-gatherer societies that inhabited the area until the early twentieth century. The central theme is the study of technological organization as an approach to the management strategies of biotic and abiotic resources, as well as the occupation of space, considering the different environments represented in the area and the differential supply of resources. As a general framework, the book proposes instrumental methodologies that allow us to look at the characterization of the social and economic organization of hunter-gatherer societies from the point of view of the analysis of natural resources management, the resources introduced by Europeans and the spatial organization of technical activities.