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Nanomaterials are able to penetrate nanoscale pores of tissues,
possess prolonged circulation, enter cells, and have increased
surface area per volume allowing for greater drug loading. For
these reasons, nanomaterials are finding numerous uses in medicine
including fighting cancer, promoting tissue regeneration, reversing
aging, inhibiting infection, limiting inflammation or scar tissue
growth, and many others. This book describes the engineering
applications and challenges of using nanostructured surfaces and
nanomaterials in healthcare. Topics covered include biomimetic
coating of calcium phosphates on Ti metals; surface modifications
of orthopedic implant materials using an electroplating process;
design, fabrication and application of carbon-based nano
biomaterials; usage of stem cells in bone and cartilage tissue
engineering; nanobiomaterials and 3D bioprinting for osteochondral
regeneration; self- assembled peptide hydrogels for biomedical
applications; antimicrobial properties of nanomaterials;
nanoparticle enhanced radiation therapy for bacterial infection;
nanomaterials used in implant technology and their toxicity;
challenges of risk assessment of nanomaterials in consumer products
and current regulatory status; and the clinical rationale for
silicon nitride bioceramics in orthopedics. With contributions from
an international selection of researchers this book is essential
reading for researchers in industry and academia working at the
interfaces of healthcare, engineering and nanotechnology.
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