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Our environment is loaded with the toxicants and heavy metals are
incriminated for toxicological influences. A reproductive toxicant
may interfere with the sexual functioning or reproductive ability
of exposed individuals from puberty throughout adulthood. Cadmium
is a ubiquitous environmental pollutant that has the potential to
disrupt tissue development and function. It has been associated
with the male reproductive toxicity. The present study has been
designed to investigate the effects of cadmium chloride (CdCl2) on
the body weights and plasma testosterone level of adult male
rabbits (Oryctolagus cuniculus). Cadmium has manifested its effects
through reduction in mean body weights of treated animals. The
androgenic profile of animals was also disrupted. The necrosis of
testicular vasculature is insinuated for disruption of testosterone
synthesis ultimately leading to low plasma testosterone level.
Therefore, it can be conclusively stated that cadmium is a
potentially hazardous heavy metal that adversely affects the
reproductive biology of the males and interferes with the androgen
production and regulation.
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