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This volume of the Keio University International Symposia for Life
Sciences and Medicine contains the proceedings of the 13th
symposium held under the sponsorship of the Keio University Medical
Science Fund. The fund was est- lished by the generous donation of
the late Dr. Mitsunada Sakaguchi. The Keio University International
Symposia for Life Sciences and Medicine constitute one of the core
activities sponsored by the fund,of which the objective is to
contribute to the international community by developing human
resources, promoting scienti?c knowledge, and encouraging mutual
exchange. Each year, the Committee of the International Symposia
for Life Sciences and Medicine selects the most signi?cant
symposium topics from applications received from the Keio medical
community. The publication of the proce- ings is intended to
publicize and distribute the information arising from the lively
discussions of the most exciting and current issues presented
during the symposium. On behalf of the Committee, I am most
grateful to the late Dr. Sakaguchi, who made the series of symposia
possible. We are also grateful to the prominent speakers for their
contribution to this volume. In addition, we would like to
acknowledge the ef?cient organizational work performed by the
members of the program committee and the staff of the fund. Naoki
Aikawa, M. D. , D. M. Sc. , F. A. C. S.
This volume of the Keio University International Symposia for Life
Sciences and Medicine contains the proceedings of the 13th
symposium held under the sponsorship of the Keio University Medical
Science Fund. The fund was est- lished by the generous donation of
the late Dr. Mitsunada Sakaguchi. The Keio University International
Symposia for Life Sciences and Medicine constitute one of the core
activities sponsored by the fund,of which the objective is to
contribute to the international community by developing human
resources, promoting scienti?c knowledge, and encouraging mutual
exchange. Each year, the Committee of the International Symposia
for Life Sciences and Medicine selects the most signi?cant
symposium topics from applications received from the Keio medical
community. The publication of the proce- ings is intended to
publicize and distribute the information arising from the lively
discussions of the most exciting and current issues presented
during the symposium. On behalf of the Committee, I am most
grateful to the late Dr. Sakaguchi, who made the series of symposia
possible. We are also grateful to the prominent speakers for their
contribution to this volume. In addition, we would like to
acknowledge the ef?cient organizational work performed by the
members of the program committee and the staff of the fund. Naoki
Aikawa, M. D. , D. M. Sc. , F. A. C. S.
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