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This fully updated book collects numerous data mining techniques,
reflecting the acceleration and diversity of the development of
data-driven approaches to the life sciences. The first half of the
volume examines genomics, particularly metagenomics and
epigenomics, which promise to deepen our knowledge of genes and
genomes, while the second half of the book emphasizes metabolism
and the metabolome as well as relevant medicine-oriented subjects.
Written for the highly successful Methods in Molecular Biology
series, chapters include the kind of detail and expert
implementation advice that is useful for getting optimal results.
Authoritative and practical, Data Mining for Systems Biology:
Methods and Protocols, Second Edition serves as an ideal resource
for researchers of biology and relevant fields, such as medical,
pharmaceutical, and agricultural sciences, as well as for the
scientists and engineers who are working on developing data-driven
techniques, such as databases, data sciences, data mining,
visualization systems, and machine learning or artificial
intelligence that now are central to the paradigm-altering
discoveries being made with a higher frequency.
The post-genomic revolution is witnessing the generation of
petabytes of data annually, with deep implications ranging across
evolutionary theory, developmental biology, agriculture, and
disease processes. Data Mining for Systems Biology: Methods and
Protocols, surveys and demonstrates the science and technology of
converting an unprecedented data deluge to new knowledge and
biological insight. The volume is organized around two overlapping
themes, network inference and functional inference. Written in the
highly successful Methods in Molecular Biology (TM) series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible protocols, and key tips on troubleshooting and
avoiding known pitfalls. Authoritative and practical, Data Mining
for Systems Biology: Methods and Protocols also seeks to aid
researchers in the further development of databases, mining and
visualization systems that are central to the paradigm altering
discoveries being made with increasing frequency.
The post-genomic revolution is witnessing the generation of
petabytes of data annually, with deep implications ranging across
evolutionary theory, developmental biology, agriculture, and
disease processes. "Data Mining for Systems Biology: Methods and
Protocols," surveys and demonstrates the science and technology of
converting an unprecedented data deluge to new knowledge and
biological insight. The volume is organized around two overlapping
themes, network inference and functional inference. Written in the
highly successful "Methods in Molecular Biology " series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible protocols, and key tips on troubleshooting and
avoiding known pitfalls.
Authoritative and practical, "Data Mining for Systems Biology:
Methods and Protocols" also seeks to aid researchers in the further
development of databases, mining and visualization systems that are
central to the paradigm altering discoveries being made with
increasing frequency."
This volume contains papers presented at the 18th International
Conference on Genome Informatics (GIW 2007) held at the Biopolis,
Singapore from December 3 to 5, 2007. The GIW Series provides an
international forum for the presentation and discussion of original
research papers on all aspects of bioinformatics, computational
biology and systems biology. Its scope includes biological sequence
analysis, protein folding prediction, gene regulatory network,
clustering algorithms, comparative genomics, and text mining.
Boasting a history of 18 years, GIW is likely the longest-running
international bioinformatics conference.A total of 16 papers were
selected for presentation at GIW 2007 and inclusion in this book.
The notable authors include Ming Li (University of Waterloo,
Canada), Minoru Kanehisa (Kyoto University, Japan), Vladimir
Kuznetsov (Genome Institute of Singapore), Tao Jiang (UC Riverside,
USA), Christos Ouzounis (European Bioinformatics Institute, UK),
and Satoru Miyano (University of Tokyo, Japan). In addition, this
book contains abstracts from the five invited speakers: Frank
Eisenhaber (Bioinformatics Institute, Singapore), Sir David Lane
(Institute of Molecular and Cell Biology, Singapore), Hanah
Margalit (The Hebrew University of Jerusalem, Israel), Lawrence
Stanton (Genome Institute of Singapore), and Michael Zhang (Cold
Spring Harbor Laboratory, USA).
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