PET/CT holds great promise for the management of many types of infection and inflammation.? This issue discusses many of these uses, starting with arthroplasty-associated infection.? FDG PET/CT also has utility in inflammatory bowel disease.? This issue also discusses the utilization of FDG PET and PET/CT in the evaluation of diabetic foot, and in monitoring therapeutic effect in patients without malignancy. PET/CT is reviewed regarding its use in patients with sarcoidosis or IgG4 disease.? Also covered is the application of FDG PET/CT in detecting the source of fever of unknown origin. Artherosclerosis and vasculitis can be assessed by PET/CT and FDG PET/CT can also be used in the management of severe infection in patients with malignancies.? Finally, the issue discusses the use of PET and PET/CT in the evaluation of osteomyelitis.

Now that the applications of positron emission tomography (PET) are becoming more clearly understood, PET is now being used in pediatric population. Important considerations in its use on children are patient preparation and radiation exposure. This issue reviews the use of PET to image children with Hodgkin and non-Hodgkin lymphoma, brain tumors, and inflammatory bowel disease, among other conditions. Also included is the use of PET to assess response to therapy.

This issue of PET Clinics focuses on PET Imaging in Pediatric Patients and is edited by Drs. Hongming Zhuang and Abass Alavi. Articles will include: Promising New PET tracers in the evaluation of pediatric disease; F-DOPA PET/CT in the management of congenital hyperinsulinism; Emerging roles of PET/MRI in pediatric hospital; Roles of FDG PET/CT in the management of posttransplant lymphoproliferative disease in pediatric patient; FDG-PET/CT in the management of pediatric lymphoma; Preparation and logistic consideration in performing PET/CT and PET/MRI in pediatric patients; PET/CT in the evaluation of FUO and infectious/inflammatory disease in pediatric patients; Roles of PET/CT in the evaluation of neuroblastoma; Potential Roles of Total Body Imaging in Pediatric Diseases and Disorders; PET/CT in the Management of Pediatric Sarcomas; Pediatric Cardiac PET Imaging; Dosimetry between PET/CT and PET/MRI: Implications in Pediatric Imaging; Essential Role of Global Disease Assessment in Assessing Systemic Disorders, and more!