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An international symposium titled "Functional Morphology of
Neuroendocrine Systems: Evolutionary and Environmental Aspects" was
held on the occasion of the 60th birthday of Professor Andreas
Oksche, head of the Department of Anatomy and Cytobiology, Justus
Liebig University, Giessen, FRG. This volume containing the texts
of the plenary lectures and the abstracts of poster contributions
presented at the symposium on July 30-August 1, 1986 in Giessen,
reflects the rapid expansion of the field of neuroendocrinology.
New insights into the interactions between neurons acting as
endocrine cells and conventional neurons have been gained by the
use of newly developed neurobiological techniques (e. g. , immuno-
cytochemistry, tracing of neuronal connections by means of
anterograde and retrograde axonal transport of identified molec-
ules, electrophysiological recordings in vivo and in vitro). The
findings of the past few years have extended the fundamental
concept of neurosecretion introduced by Ernst and Berta Scharrer in
close cooperation with Wolfgang Bargmann. An important landmark was
the discovery that neurons containing classical neurosecretory
products not only project to neurohemal release organs but also
establish hypothalamic and extrahypothalamic neuro-neuronal
contacts. In some of these neurons monoamine transmitters are known
to co-exist with opioid and other neuro- peptides. Different types
of transmitters may even be co-localized in the same dense core
vesicles. The use of extremely sensitive techniques which allow the
detection of minute quantities of messenger substances has provided
evidence that several of these substances have been well preserved
in the course of evolution.
70 years after the discovery of secretory neurons, internationally
leading experts gathered to discuss the latest developments in
neuropeptide research and endocrinology, concentrating on the
molecular, cellular, supracellular and systemic aspects. A variety
of neuropeptidergic systems are considered under comparative and
evolutionary aspects.
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