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Neurotoxicology (Hardcover, 3rd edition): G. Jean Harry, Hugh A. Tilson Neurotoxicology (Hardcover, 3rd edition)
G. Jean Harry, Hugh A. Tilson
R5,356 Discovery Miles 53 560 Ships in 12 - 17 working days

This new edition presents an integrated approach to neurotoxicology, the study of organisms' responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects - from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs similar to neurodegenerative disorders such as Parkinson's or Alzheimer's disease. It is an essential resource for understanding the sites and mechanisms of neurotoxicity, for formulating testable hypotheses about the effects of neurotoxicants, and for improving the risk assessment process.
Key topics include:
completely revised content with new contributors and new illustrations, including a full-color insertnew state-of-the-science technologiesnew areas of research and alternative model systemsup-to-date coverage of epidemiology, model systems, mechanisms of action, assessment of risk, and cellular approaches to neurotoxicologymetabolic influences on neurotoxicityrole of free radical formation in neurotoxicityinteraction between chemicals and trophic factorsendocrine disruptorsapoptosis in neurotoxicityin vivo brain imagingadvances in measuring cognitive functionadvances in developing quantitative models for neurotoxicology/risk assessment

Introduction to Neurobehavioral Toxicology - Food and Environment (Hardcover): Hugh A. Tilson, R.M.A. Jaspers, L.M.W. Kornet,... Introduction to Neurobehavioral Toxicology - Food and Environment (Hardcover)
Hugh A. Tilson, R.M.A. Jaspers, L.M.W. Kornet, J.M. Van Ree
R5,676 Discovery Miles 56 760 Ships in 12 - 17 working days

Introduction to Neurobehavioral Toxicology: Food and Environment examines the effects of chemicals on the central and peripheral nervous system and the subsequent changes in behavior, with a focus on the toxicity of food components and behavioral effects of environmental toxicants. Topics addressed include acute and chronic effects; reversible and irreversible consequences; functional disorders of the nervous system; neurobehavioral dysfunctions; and the underlying neurobiological mechanisms.

Neurodegeneration Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 1999): Jean Harry, Hugh A. Tilson Neurodegeneration Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 1999)
Jean Harry, Hugh A. Tilson
R2,961 Discovery Miles 29 610 Ships in 10 - 15 working days

Rapid advances in our understanding of basic cell biological processes and of the molecular mechanisms of cell function and dysfunction have led to an increasing interest in utilizing these approaches in neurobiological research. Efforts in the most rapidly advancing areas are multidisciplinary and the o- come of contributions from many investigators employing a variety of te- niques to address a specific problem. Although a strong basis in fundamental neurobiological concepts is essential for each researcher, the ability to apply new techniques and approaches to the examinination of both cellular and molecular processes requires knowledge of a wide variety of methodologies. The objective of Neurodegeneration Methods and Protocols is to develop an understanding, appreciation, and technical ability in various cellular and molecular techniques for studying many aspects of nervous system cell bi- ogy. The protocols in this volume span a multidisciplinary range of cellular and molecular approaches, and should allow investigators to address research questions directed toward understanding nervous system function, injury, degeneration, and the repair/regenerative process.

Neurodegeneration Methods and Protocols (Hardcover, 1999 ed.): Jean Harry, Hugh A. Tilson Neurodegeneration Methods and Protocols (Hardcover, 1999 ed.)
Jean Harry, Hugh A. Tilson
R3,156 Discovery Miles 31 560 Ships in 10 - 15 working days

Rapid advances in our understanding of basic cell biological processes and of the molecular mechanisms of cell function and dysfunction have led to an increasing interest in utilizing these approaches in neurobiological research. Efforts in the most rapidly advancing areas are multidisciplinary and the o- come of contributions from many investigators employing a variety of te- niques to address a specific problem. Although a strong basis in fundamental neurobiological concepts is essential for each researcher, the ability to apply new techniques and approaches to the examinination of both cellular and molecular processes requires knowledge of a wide variety of methodologies. The objective of Neurodegeneration Methods and Protocols is to develop an understanding, appreciation, and technical ability in various cellular and molecular techniques for studying many aspects of nervous system cell bi- ogy. The protocols in this volume span a multidisciplinary range of cellular and molecular approaches, and should allow investigators to address research questions directed toward understanding nervous system function, injury, degeneration, and the repair/regenerative process.

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