The presence of high risk HPV that were possibly responsible of cervical cancer in the Sudan.Therefore, this book invesigated the possible relation between High risk Human Papilloma virus and cervical cancer in addition to how far HR-HPV contribute to gynecologic compalains among Sudanese Women. This in addition to frquencies of other bacterial, parasitic and fungal infections that may present in cervical smears. Furthermore, Pat. test, the most common measure in this context was evaluted for its specificity and sensitivity measures in comparison to In-Situ Hybridization as gold standard technique for Identification of HPV.