This title primarily focuses on the functional mechanisms and roles of Ca2+ channels in the central nervous system, and the effects of a Ca antagonists on cytosolic Ca2+ by blocking voltage sensitive channels.;These findings are an important contribution to understanding the mechanisms of brain dysfunctions, including Alzheimer's disease, cerebral ischemia, and effective disorders, as well as the effects of cytosolic Ca2+ modulators on neuronal cell death.;Additional reported are the results of clinical trials using typical and atypical Ca antagonists in the treatment of neuropsychiatric diseases.;An essential reference to some of the most current and vital research into Ca antagonists as therapeutic agents, this monograph is invaluable for all clinical and preclinical researchers active in the multidisciplinary fields of neuroscience, including psychopharmacology, molecular biology, behaviourial pharmacology, neuropharmacology, and electrophysiology and immunology.;Investigators of cytosolic Ca2+ dynamics and brain dysfunction will specially find this book useful towards the development of novel drugs to treat neuropsychiatric diseases.