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Endocrinology, as a discipline, was a late arrival in the corpus of
established subjects. Its growth in recent years has been
prodigious, extending from mor phology to molecular levels. Most of
the major endocrine glands were noted by the early anatomists,
although the adrenal glands were not described until 1563 by
Bartholomaeus Eustachius (1520-1574). On the other hand,
elucidation of the function of these glands was extremely slow. Key
work by A. A. Berthold (1849), although overlooked at the time,
showed that comb atrophy in castrated fowl was prevented by testis
transplantation. The idea that glands produced substances reach ing
the bloodstream directly and not via excretory ducts stemmed from
Claude Bernard, who first used the term internal secretion in 1855.
The clinical observa tions of Thomas Addison at Guy's
Hospital-published as a monograph in 1855 entitled The
Constitutional and Local Effects of Disease of the Suprarenal
Capsules -were seminal. However, the stimulus of this early
research did not bring imme diate widespread further
investigations. Upon the discovery of secretin in 1902, Bayliss and
Starling considered the term "internal secretion" to be clumsy, and
the term "hormone" was coined (from OQ UW-1 excite or arouse) and
it was first used by Starling in his Croonian of 1905."
Endocrinology, as a discipline, was a late arrival in the corpus of
established subjects. Its growth in recent years has been
prodigious, extending from mor phology to molecular levels. Most of
the major endocrine glands were noted by the early anatomists,
although the adrenal glands were not described until 1563 by
Bartholomaeus Eustachius (1520-1574). On the other hand,
elucidation of the function of these glands was extremely slow. Key
work by A. A. Berthold (1849), although overlooked at the time,
showed that comb atrophy in castrated fowl was prevented by testis
transplantation. The idea that glands produced substances reach ing
the bloodstream directly and not via excretory ducts stemmed from
Claude Bernard, who first used the term internal secretion in 1855.
The clinical observa tions of Thomas Addison at Guy's
Hospital-published as a monograph in 1855 entitled The
Constitutional and Local Effects of Disease of the Suprarenal
Capsules -were seminal. However, the stimulus of this early
research did not bring imme diate widespread further
investigations. Upon the discovery of secretin in 1902, Bayliss and
Starling considered the term "internal secretion" to be clumsy, and
the term "hormone" was coined (from OQ UW-1 excite or arouse) and
it was first used by Starling in his Croonian of 1905."
Originally published in 1957, this book provides a comprehensive
account of the workings of the adrenal cortex in various vertebrate
species. Chester Jones also covers the embryological development of
the kidneys and suggests how the structure and function of the
adrenal glands are related to one another in vertebrates. This book
will be of value to anyone with an interest in the adrenal cortex
or the history of science and zoology.
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