The Coronavirus pandemic that began in 2019 brought to the fore, the presence of a significant minority of individuals who strongly oppose vaccination. This opposition is by no means recent. Ever since the very first attempts to immunize individuals, opposition has been intense in some societies. The reasons for this opposition range from religious to political to medical. Although vaccines have eliminated smallpox and largely eliminated polio and measles, opposition to vaccination persists and, in some countries, has grown stronger. The History of Vaccine Hesitancy seeks to describe the history of this opposition as well as its changing rationale over the years and in different societies. The discussion may ultimately provide some suggestions for reducing hesitancy in the future.

Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.

Great American Diseases: Their Effects on the Course of North American History presents medical history as it pertains to the major infectious diseases of North America. The book is designed to provide an interesting and engaging introduction to microbiology, immunology and epidemiology. With the advent of COVID-19, this book will serve as a reference on the history of previous epidemics. The book presents pandemics in an easy-to-read volume and provides concise chapters on the history of a disease, progression of understanding on the pathogen (agent of the disease), and their social ramifications through the history of North America.

Learn to treat allergic diseases in animals using the latest protocols, procedures, and studies! Allergies and Hypersensitivity Disease in Animals provides an all-in-one review of allergic diseases in dogs, cats, horses, and livestock species. Addressing this growing problem, the book covers key topics such as signs of allergies and hypersensitivity disease, the route by which antigens enter the body, the major mediators of allergies, allergic reactions including anaphylaxis and atopic and contact dermatitis, and diagnosis and treatment. Written by noted veterinary author Ian R. Tizard, this evidence-based reference includes an enhanced eBook with print purchase, with access to a fully searchable version of the text available on a variety of devices. It's a must-have for every veterinary practice! Advanced immunology reference highlights the essential topics relating to veterinary allergies and hypersensitivity. Comprehensive coverage provides a single-source review of allergic diseases in dogs, cats, horses and livestock species. Clear guidelines are provided for treatment protocols and diagnostic procedures, all based on the latest pathogenesis studies. Expert author Ian R. Tizard is a well-established veterinary writer who is world-renowned on the topic of vaccinations, immunology, and allergies in veterinary medicine. Consistent organization for each chapter - Introduction, Pathogenesis, Allergens, Clinical Disease, Diagnosis, and Treatment - supports evidence-based veterinary care. Basic science chapters are useful for exam review and as clinical companion resources. Enhanced eBook provides access to a fully searchable version of the entire text, making it available on a variety of devices, and is included with each new print purchase.

With nearly 100 different autoimmune diseases reported to occur in domestic animal species, this evidence-based clinical reference is a must-have for every veterinary practice! Autoimmune Diseases in Domestic Animals, from noted veterinary author Ian R. Tizard, sheds light on both common and rare conditions, including skin diseases, diabetes mellitus, thyroiditis, and hemolytic anemia. Convenient and portable, this single-source review addresses autoimmune diseases in dogs, cats, horses, and livestock species with comprehensive coverage of treatment protocols, diagnostic procedures, and the latest pathogenesis studies. All-in-one guide covers the basic science, clinical presentation, and treatment of this set of increasingly prevalent animal diseases. Comprehensive information for each disease prepares students to communicate effectively with clients. Reviews of the most recent relevant literature provide a clearer understanding of complex autoimmune diseases. Detailed coverage facilitates the accurate diagnosis and rational treatment of immunologic diseases. Information on autoimmune mouse strains and other animal models meets the needs of comparative immunology and research students. Expert author Ian R. Tizard is a well-established veterinary writer who is world-renowned on the topic of immunology in veterinary medicine.

Both a theoretical text and a practical handbook, Vaccines for Veterinarians is the first of its kind to bring the basic science of animal vaccination and the practical details of vaccine use together in one single volume. From the first chapter on the history of vaccination and the triumph of rinderpest eradication to the last chapter on the rapidly emerging field of cancer vaccines, this book offers a truly comprehensive grounding in established and emerging vaccines for both major and minor species. Specific topics include viral vectored vaccines, DNA-plasmid vaccines, RNA vaccines, reverse vaccinology, the complexities of adjuvant use, vaccine failures and adverse events, vaccine production and regulation, robotic vaccination machines, contraceptive and production-enhancing vaccines, and so much more. At a time when resistance to human vaccination is receiving much publicity, this evidence-based book is the ideal counter to ill-informed speculation - serving as a timely reminder that vaccination is essential for the control of infectious diseases in animals. Well-respected and experienced veterinary author, Ian Tizard, provides expert guidance on the topic of vaccinations and immunology in veterinary medicine. Expert Consult site offers an online version of the book, making it easy to search the entire book electronically. The latest information on viral vectored vaccines keeps you up-to-date on the topic as well as the properties and relative advantages of currently used vectors in animal vaccines. Survey of vaccine responses covers the different mechanisms by which the immune system responds to different types of vaccines. Inclusion of the latest vaccine technologies discusses the advantages and disadvantages of DNA-plasmid vaccines, RNA vaccines, and more. Coverage of adverse events and hypersensitivities includes the best ways to treat them and report them. Coverage of passive immunization discusses the growing use of therapeutic monoclonal antibodies in veterinary medicine. Coverage of immunotherapy includes recent improvements and new products in both active and passive immunotherapy against animal cancers.