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" Principles of Cloning, Second Edition" is the fully revised
edition of the authoritative book on the science of cloning. The
book presents the basic biological mechanisms of how cloning works
and progresses to discuss current and potential applications in
basic biology, agriculture, biotechnology, and medicine. Beginning
with the history and theory behind cloning, the book goes on to
examine methods of micromanipulation, nuclear transfer, genetic
modification, and pregnancy and neonatal care of cloned animals.
The cloning of various species-including mice, sheep, cattle, and
non-mammals-is considered as well. The Editors have been involved
in a number of breakthroughs using cloning technique, including the
first demonstration that cloning works in differentiated cells done
by the Recipient of the 2012 Nobel Prize for Physiology or Medicine
- Dr John Gurdon; the cloning of the first mammal from a somatic
cell - Drs Keith Campbell and Ian Wilmut; the demonstration that
cloning can reset the biological clock - Drs Michael West and
Robert Lanza; the demonstration that a terminally differentiated
cell can give rise to a whole new individual - Dr Rudolf Jaenisch
and the cloning of the first transgenic bovine from a
differentiated cell - Dr Jose Cibelli. The majority of the
contributing authors are the principal investigators on each of the
animal species cloned to date and are expertly qualified to present
the state-of-the-art information in their respective areas.
First and most comprehensive book on animal cloning, 100%
revisedDescribes an in-depth analysis of current limitations of the
technology and research areas to exploreOffers cloning applications
on basic biology, agriculture, biotechnology, and medicine "
A timely investigation into the ethics, history, and potential of
human cloning from Professor Ian Wilmut, who shocked scientists,
ethicists, and the public in 1997 when his team unveiled Dolly that
very special sheep who was cloned from a mammary cell. With
award-winning science journalist Roger Highfield, Wilmut explains
how Dolly launched a medical revolution in which cloning is now
used to make stem cells that promise effective treatments for many
major illnesses. Dolly's birth also unleashed an avalanche of
speculation about the eventuality of cloning babies, which Wilmut
strongly opposes. However, he does believe that scientists should
one day be allowed to combine the cloning of human embryos with
genetic modification to free families from serious hereditary
disease. In effect, he is proposing the creation of genetically
altered humans."
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